Prognostic Value of the Preoperative ALBI Score for Postoperative Bleeding After Isolated CABG
- 1Department of Cardiovascular Surgery, İzmir Bakırçay University, Menemen 35665, Turkey
- 2Department of Cardiovascular Surgery, İstanbul Mehmet Akif Ersoy Thoracic and Cardiovascular Surgery Hospital, Istanbul 34303, Turkey
Abstract
Background: The Albumin–Bilirubin (ALBI) score is an easy-to-use, objective marker of liver synthetic function that has demonstrated prognostic value in various cardiovascular conditions. However, its role in predicting postoperative bleeding after CABG has not been previously investigated. Methods: Patients were divided into two groups according to their median preoperative ALBI score (−2.97): Low ALBI (n = 78) and High ALBI (n = 79). The primary outcome was excessive postoperative bleeding, defined as cumulative drainage exceeding 1000 mL within the first 24 postoperative hours. Secondary outcomes included transfusion requirements, mechanical ventilation duration, and length of hospital stay. Correlation and regression analyses were performed to assess the relationship between the ALBI score and postoperative bleeding. Results: The High ALBI group demonstrated a significantly greater postoperative drainage volume (450 [350–700] mL vs. 350 [300–487.5] mL, p = 0.007), higher erythrocyte transfusion (p = 0.001) and fresh frozen plasma transfusion requirements (p = 0.034), and prolonged mechanical ventilation duration (p < 0.001) and hospital stay (p = 0.003) compared to the Low ALBI group. Spearman correlation analysis revealed a significant positive correlation between the ALBI score and drainage volume (rho = 0.272, p < 0.001), and thus the ALBI score was identified as a significant predictor of excessive postoperative bleeding exceeding 1000 mL (OR: 5.93, 95% CI: 1.63–21.60, p = 0.007). Conclusions: The preoperative ALBI score is an easy-to-use and readily available tool that may serve as an effective adjunct for identifying patients at an elevated risk of postoperative bleeding prior to isolated CABG.
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BibTeX
@article{ozbakkaloglu2026prognostic,
title = {{Prognostic Value of the Preoperative ALBI Score for Postoperative Bleeding After Isolated CABG}},
author = {Alper Özbakkaloğlu and Önder Turgut Bozkurt and Dağlar Cansu and Enver Oğuzhan Metehan and Tufan Erdem Emeklikol and Safa Göde and Şahin Bozok},
journal = {Journal of Clinical Medicine},
year = {2026},
month = oct,
doi = {10.3390/jcm15218370},
url = {https://www.mdpi.com/2077-0383/15/21/8370},
note = {CC BY 4.0},
}
RIS
TY - JOUR
TI - Prognostic Value of the Preoperative ALBI Score for Postoperative Bleeding After Isolated CABG
AU - Alper Özbakkaloğlu
AU - Önder Turgut Bozkurt
AU - Dağlar Cansu
AU - Enver Oğuzhan Metehan
AU - Tufan Erdem Emeklikol
AU - Safa Göde
AU - Şahin Bozok
PY - 2026
DA - 2026/10/27
JO - Journal of Clinical Medicine
DO - 10.3390/jcm15218370
UR - https://www.mdpi.com/2077-0383/15/21/8370
AB - Background: The Albumin–Bilirubin (ALBI) score is an easy-to-use, objective marker of liver synthetic function that has demonstrated prognostic value in various cardiovascular conditions. However, its role in predicting postoperative bleeding after CABG has not been previously investigated. Methods: Patients were divided into two groups according to their median preoperative ALBI score (−2.97): Low ALBI (n = 78) and High ALBI (n = 79). The primary outcome was excessive postoperative bleeding, defined as cumulative drainage exceeding 1000 mL within the first 24 postoperative hours. Secondary outcomes included transfusion requirements, mechanical ventilation duration, and length of hospital stay. Correlation and regression analyses were performed to assess the relationship between the ALBI score and postoperative bleeding. Results: The High ALBI group demonstrated a significantly greater postoperative drainage volume (450 [350–700] mL vs. 350 [300–487.5] mL, p = 0.007), higher erythrocyte transfusion (p = 0.001) and fresh frozen plasma transfusion requirements (p = 0.034), and prolonged mechanical ventilation duration (p < 0.001) and hospital stay (p = 0.003) compared to the Low ALBI group. Spearman correlation analysis revealed a significant positive correlation between the ALBI score and drainage volume (rho = 0.272, p < 0.001), and thus the ALBI score was identified as a significant predictor of excessive postoperative bleeding exceeding 1000 mL (OR: 5.93, 95% CI: 1.63–21.60, p = 0.007). Conclusions: The preoperative ALBI score is an easy-to-use and readily available tool that may serve as an effective adjunct for identifying patients at an elevated risk of postoperative bleeding prior to isolated CABG.
SN - 2077-0383
ER -