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Peer-reviewedCC BYJournal of the Pakistan Medical Association

Lighting the Future of Neuro-Oncology: Laser Interstitial Thermal Therapy for Brain Tumours

4 affiliations
  1. 1Department of Surgery, University College of Medicine and Dentistry, Lahore;
  2. 2Medical Student, University College of Medicine and Dentistry, Lahore.;
  3. 3Department of Neurosurgery, Memon Medical Institute Hospital, Karachi;
  4. 4Department of Neurosurgery, The Aga Khan University Hospital, Karachi.

Abstract

Laser interstitial thermal therapy (LITT) is an image-guided neurosurgical technique that destroys pathological brain tissue through controlled thermal energy delivered via stereotactic catheter placement. It is primarily used for deep, recurrent, or unsuitable intracranial lesions, including high-grade gliomas, metastatic deposits, and treatmentrelated necrosis. This review aims to summarize the current evidence regarding the indications, clinical outcomes, procedural considerations, and complications of Laser Interstitial Thermal Therapy in the management of brain tumours.

Keywords: Laser interstitial thermal therapy, minimally invasive neurosurgery, brain tumour management, MRIguided laser ablation, glioblastoma management, thermal coagulation.

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BibTeX
@article{ali2026lighting,
  title = {{Lighting the Future of Neuro-Oncology: Laser Interstitial Thermal Therapy for Brain Tumours}},
  author = {Eisha Abid Ali and Rahamah Arshad and Ahmad Sohail and Aima Vaqas and Quratulain Tariq and M Shahzad Shamim},
  journal = {Journal of the Pakistan Medical Association},
  year = {2026},
  month = nov,
  doi = {10.47391/jpma.26-93},
  url = {https://doi.org/10.47391/jpma.26-93},
  note = {CC BY},
}
RIS
TY  - JOUR
TI  - Lighting the Future of Neuro-Oncology: Laser Interstitial Thermal Therapy for Brain Tumours
AU  - Eisha Abid Ali
AU  - Rahamah Arshad
AU  - Ahmad Sohail
AU  - Aima Vaqas
AU  - Quratulain Tariq
AU  - M Shahzad Shamim
PY  - 2026
DA  - 2026/11/01
JO  - Journal of the Pakistan Medical Association
DO  - 10.47391/jpma.26-93
UR  - https://doi.org/10.47391/jpma.26-93
AB  - Laser interstitial thermal therapy (LITT) is an image-guided neurosurgical technique that destroys pathological brain tissue through controlled thermal energy delivered via stereotactic catheter placement. It is primarily used for deep, recurrent, or unsuitable intracranial lesions, including high-grade gliomas, metastatic deposits, and treatmentrelated necrosis. This review aims to summarize the current evidence regarding the indications, clinical outcomes, procedural considerations, and complications of Laser Interstitial Thermal Therapy in the management of brain tumours.  Keywords: Laser interstitial thermal therapy, minimally invasive neurosurgery, brain tumour management, MRIguided laser ablation, glioblastoma management, thermal coagulation.
SN  - 0030-9982
ER  -