Prescribing, Medication Adherence, and Blood Pressure Goal Achievement Among Middle-to-Older Age Adults in a Primary Care Setting.
7 affiliations
- 1Pharmaceutical Care Research Group School of Pharmacy University College Cork Cork Ireland ucc.ie.
- 2Clinical Pharmacy Department Faculty of Pharmacy Minia University Minia Egypt minia.edu.eg.
- 3School of Public Health University College Cork Cork Ireland ucc.ie.
- 4MRC Integrative Epidemiology Unit at the University of Bristol University of Bristol Bristol UK bristol.ac.uk.
- 5Population Health Sciences Bristol Medical School University of Bristol Bristol UK bristol.ac.uk.
- 6School of Medicine University College Cork Cork Ireland ucc.ie.
- 7Pharmacy Department Bon Secours Hospital Cork Ireland bonsecours.com.
Abstract
Blood pressure (BP) control among hypertensive people remains inadequate. This study aims to assess BP goal achievement among people prescribed antihypertensives, to examine medication nonadherence, and to identify demographics associated with goal achievements and medication nonadherence in this population. This was a cross-sectional analysis of the Mitchelstown Cohort Study Rescreen data. Goal achievement was assessed in accordance with the 2013 European guidelines, the guidelines in place during data collection. A validated, self-reported 3-item medication nonadherence questionnaire was used, with a mean score ranging from 1 (Perfect Adherence) to 5 (Perfect Nonadherence). Nonadherence was defined as mean score > 1. Multiple imputation was used to impute missing data on covariates and outcomes. A sensitivity analysis was performed to assess the consistency of results by applying the 2024 European guideline recommendations. Multivariable logistic regression analysis was used to identify the factors associated with BP goal achievements and medication nonadherence. Antihypertensives were prescribed to 567 participants. Based on imputed data, 63.8% of these achieved 2013 BP goal. Mean medication nonadherence score was 1.6 (SE ± 0.06), with 34.8% participants being nonadherent. Having multiple antihypertensives pills was associated with lower likelihood of achieving BP goals. In the sensitivity analysis, 38.4% achieved 2024 BP goal and in multivariable analysis, being overweight or obese was associated with not achieving the 2024 goals. The study highlights the gap between guideline BP goals and achieving these goals in real world practice. Key patient and medication factors were identified that could guide efforts to improve BP goal achievement. Trial Registration: ClinicalTrials.gov identifier: NCT03191227.
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BibTeX
@article{elhiny2026prescribing,
title = {{Prescribing, Medication Adherence, and Blood Pressure Goal Achievement Among Middle-to-Older Age Adults in a Primary Care Setting.}},
author = {Rehab Elhiny and Linda M O'Keeffe and Tarun Das and Edel Burton and Seán R Millar and Stephen Byrne and Maria Donovan and Margaret Bermingham},
journal = {International journal of hypertension},
year = {2026},
month = nov,
doi = {10.1155/ijhy/1613515},
url = {https://europepmc.org/article/MED/42999744},
note = {CC BY},
}
RIS
TY - JOUR
TI - Prescribing, Medication Adherence, and Blood Pressure Goal Achievement Among Middle-to-Older Age Adults in a Primary Care Setting.
AU - Rehab Elhiny
AU - Linda M O'Keeffe
AU - Tarun Das
AU - Edel Burton
AU - Seán R Millar
AU - Stephen Byrne
AU - Maria Donovan
AU - Margaret Bermingham
PY - 2026
DA - 2026/11/06
JO - International journal of hypertension
DO - 10.1155/ijhy/1613515
UR - https://europepmc.org/article/MED/42999744
AB - Blood pressure (BP) control among hypertensive people remains inadequate. This study aims to assess BP goal achievement among people prescribed antihypertensives, to examine medication nonadherence, and to identify demographics associated with goal achievements and medication nonadherence in this population. This was a cross-sectional analysis of the Mitchelstown Cohort Study Rescreen data. Goal achievement was assessed in accordance with the 2013 European guidelines, the guidelines in place during data collection. A validated, self-reported 3-item medication nonadherence questionnaire was used, with a mean score ranging from 1 (Perfect Adherence) to 5 (Perfect Nonadherence). Nonadherence was defined as mean score > 1. Multiple imputation was used to impute missing data on covariates and outcomes. A sensitivity analysis was performed to assess the consistency of results by applying the 2024 European guideline recommendations. Multivariable logistic regression analysis was used to identify the factors associated with BP goal achievements and medication nonadherence. Antihypertensives were prescribed to 567 participants. Based on imputed data, 63.8% of these achieved 2013 BP goal. Mean medication nonadherence score was 1.6 (SE ± 0.06), with 34.8% participants being nonadherent. Having multiple antihypertensives pills was associated with lower likelihood of achieving BP goals. In the sensitivity analysis, 38.4% achieved 2024 BP goal and in multivariable analysis, being overweight or obese was associated with not achieving the 2024 goals. The study highlights the gap between guideline BP goals and achieving these goals in real world practice. Key patient and medication factors were identified that could guide efforts to improve BP goal achievement. Trial Registration: ClinicalTrials.gov identifier: NCT03191227.
SN - 2090-0384
SN - 2090-0392
ER -