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Peer-reviewedCC BYJournal of surgical case reports

A 17-cm ileocecal inflammatory myofibroblastic tumor with severe inflammatory syndrome in a child: a case report

  1. 1The First Ward of the Department of General Surgery, The Second Hospital of Sanming, No. 513, Rongkang East Road, Yong'an City, Sanming, Fujian 366000, China.
  2. 2Department of Imaging, The Second Hospital of Sanming, No. 513, Rongkang East Road, Yong'an City, Sanming, Fujian 366000, China.
  3. 3Department of Pathology, The Second Hospital of Sanming, No. 513, Rongkang East Road, Yong'an City, Sanming, Fujian 366000, China.

Abstract

We present a case of a giant ileocecal inflammatory myofibroblastic tumor (IMT), which represents one of the largest pediatric colorectal IMTs reported in the literature. An 11-year-old girl presented with a 1-day history of abdominal pain and developed fever (up to 102.2°F). Laboratory evaluation revealed severe anemia (hemoglobin, 53 g/L) and marked systemic inflammatory abnormalities consistent with paraneoplastic inflammatory syndrome. Exploratory laparotomy revealed a 17 × 17 × 8 cm mass intimately adherent to the ileocecal region. Histopathological examination confirmed IMT with focal ALK positivity. The inflammatory and hematologic abnormalities improved rapidly following complete tumor resection.

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BibTeX
@article{wang202617cm,
  title = {{A 17-cm ileocecal inflammatory myofibroblastic tumor with severe inflammatory syndrome in a child: a case report}},
  author = {Junxiao Wang and Jianping Zhang and Guihua Le and Chuanqi Ren and Yihan Zhang and Ezhang Liu},
  journal = {Journal of surgical case reports},
  year = {2026},
  month = oct,
  doi = {10.1093/jscr/rjag996},
  url = {https://europepmc.org/article/PMC/PMC13725758},
  note = {CC BY},
}
RIS
TY  - JOUR
TI  - A 17-cm ileocecal inflammatory myofibroblastic tumor with severe inflammatory syndrome in a child: a case report
AU  - Junxiao Wang
AU  - Jianping Zhang
AU  - Guihua Le
AU  - Chuanqi Ren
AU  - Yihan Zhang
AU  - Ezhang Liu
PY  - 2026
DA  - 2026/10/01
JO  - Journal of surgical case reports
DO  - 10.1093/jscr/rjag996
UR  - https://europepmc.org/article/PMC/PMC13725758
AB  - We present a case of a giant ileocecal inflammatory myofibroblastic tumor (IMT), which represents one of the largest pediatric colorectal IMTs reported in the literature. An 11-year-old girl presented with a 1-day history of abdominal pain and developed fever (up to 102.2°F). Laboratory evaluation revealed severe anemia (hemoglobin, 53 g/L) and marked systemic inflammatory abnormalities consistent with paraneoplastic inflammatory syndrome. Exploratory laparotomy revealed a 17 × 17 × 8 cm mass intimately adherent to the ileocecal region. Histopathological examination confirmed IMT with focal ALK positivity. The inflammatory and hematologic abnormalities improved rapidly following complete tumor resection.
SN  - 2042-8812
ER  -