Peer-reviewedCC BYJournal of surgical case reports
A 17-cm ileocecal inflammatory myofibroblastic tumor with severe inflammatory syndrome in a child: a case report
- 1The First Ward of the Department of General Surgery, The Second Hospital of Sanming, No. 513, Rongkang East Road, Yong'an City, Sanming, Fujian 366000, China.
- 2Department of Imaging, The Second Hospital of Sanming, No. 513, Rongkang East Road, Yong'an City, Sanming, Fujian 366000, China.
- 3Department of Pathology, The Second Hospital of Sanming, No. 513, Rongkang East Road, Yong'an City, Sanming, Fujian 366000, China.
Abstract
We present a case of a giant ileocecal inflammatory myofibroblastic tumor (IMT), which represents one of the largest pediatric colorectal IMTs reported in the literature. An 11-year-old girl presented with a 1-day history of abdominal pain and developed fever (up to 102.2°F). Laboratory evaluation revealed severe anemia (hemoglobin, 53 g/L) and marked systemic inflammatory abnormalities consistent with paraneoplastic inflammatory syndrome. Exploratory laparotomy revealed a 17 × 17 × 8 cm mass intimately adherent to the ileocecal region. Histopathological examination confirmed IMT with focal ALK positivity. The inflammatory and hematologic abnormalities improved rapidly following complete tumor resection.
Related
- Case Report: Hepatic inflammatory myofibroblastic tumor versus hepatic inflammatory pseudotumor in pediatric patients
- Severe Inflammatory Response and Moderate Acute Respiratory Distress Syndrome (ARDS) in an Immunocompetent Patient With Disseminated Tuberculosis: A Case Report.
- Inflammatory Myofibroblastic Tumor of the Bladder Following Intravesical Bacillus Calmette-Guérin Therapy: A Case Report
- Acute-Onset Chronic Inflammatory Demyelinating Polyneuropathy May Manifest as Recurrent Guillain-Barré Syndrome of a Severe Refractory Case
- Reply to the Letter “Acute-Onset Chronic Inflammatory Demyelinating Polyneuropathy May Manifest as Recurrent Guillain-Barré Syndrome of a Severe Refractory Case”
BibTeX
@article{wang202617cm,
title = {{A 17-cm ileocecal inflammatory myofibroblastic tumor with severe inflammatory syndrome in a child: a case report}},
author = {Junxiao Wang and Jianping Zhang and Guihua Le and Chuanqi Ren and Yihan Zhang and Ezhang Liu},
journal = {Journal of surgical case reports},
year = {2026},
month = oct,
doi = {10.1093/jscr/rjag996},
url = {https://europepmc.org/article/PMC/PMC13725758},
note = {CC BY},
}
RIS
TY - JOUR
TI - A 17-cm ileocecal inflammatory myofibroblastic tumor with severe inflammatory syndrome in a child: a case report
AU - Junxiao Wang
AU - Jianping Zhang
AU - Guihua Le
AU - Chuanqi Ren
AU - Yihan Zhang
AU - Ezhang Liu
PY - 2026
DA - 2026/10/01
JO - Journal of surgical case reports
DO - 10.1093/jscr/rjag996
UR - https://europepmc.org/article/PMC/PMC13725758
AB - We present a case of a giant ileocecal inflammatory myofibroblastic tumor (IMT), which represents one of the largest pediatric colorectal IMTs reported in the literature. An 11-year-old girl presented with a 1-day history of abdominal pain and developed fever (up to 102.2°F). Laboratory evaluation revealed severe anemia (hemoglobin, 53 g/L) and marked systemic inflammatory abnormalities consistent with paraneoplastic inflammatory syndrome. Exploratory laparotomy revealed a 17 × 17 × 8 cm mass intimately adherent to the ileocecal region. Histopathological examination confirmed IMT with focal ALK positivity. The inflammatory and hematologic abnormalities improved rapidly following complete tumor resection.
SN - 2042-8812
ER -