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Peer-reviewedCC BYClinical case reports

Successful Thromboembolectomy for PTE in an Adolescent Patient With Catastrophic APS and SLE.

  • Azadeh Zeinab Mirzaee1
  • Bita Paknejad2
  • Aziz Eghbali3
  • Reza Shiari4
  • Niku Rahimi Afzal2
4 affiliations
  1. 1Pediatric Respiratory Diseases Research Center (PRDRC), National Research Institute of Tuberculosis and Lung Diseases (NRITLD), Masih Daneshvari Hospital, Faculty of Medicine Shahid Beheshti University of Medical Sciences Tehran Iran.
  2. 2Pediatric Respiratory Diseases Research Center (PRDRC), National Research Institute of Tuberculosis and Lung Diseases (NRITLD), Masih Daneshvari Hospital, Faculty of Medicine, Masih Daneshvari Hospital Shahid Beheshti University of Medical Sciences Tehran Iran.
  3. 3Clinical Research Development Center of Aliasghar Hospital Iran University of Medical Sciences Tehran Iran.
  4. 4Department of Pediatric Rheumatology, Mofid Children's Hospital Shahid Beheshti University of Medical Sciences Tehran Iran.
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Abstract

In a 14-year-old with antiphospholipid syndrome (APS) and lupus anticoagulant, improper switching from warfarin and low-dose aspirin to rivaroxaban led to life-threatening recurrent thrombosis, pulmonary embolism, and pulmonary hypertension. Prompt return to standard anticoagulation plus immunosuppression stabilized the condition. This case underscores that DOACs are contraindicated in high-risk APS.

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Cite

BibTeXRIS
BibTeX
@article{mirzaee2026successful,
  title = {{Successful Thromboembolectomy for PTE in an Adolescent Patient With Catastrophic APS and SLE.}},
  author = {Azadeh Zeinab Mirzaee and Bita Paknejad and Aziz Eghbali and Reza Shiari and Niku Rahimi Afzal},
  journal = {Clinical case reports},
  year = {2026},
  month = nov,
  doi = {10.1002/ccr3.73911},
  url = {https://europepmc.org/article/MED/43011232},
  note = {CC BY},
}
RIS
TY  - JOUR
TI  - Successful Thromboembolectomy for PTE in an Adolescent Patient With Catastrophic APS and SLE.
AU  - Azadeh Zeinab Mirzaee
AU  - Bita Paknejad
AU  - Aziz Eghbali
AU  - Reza Shiari
AU  - Niku Rahimi Afzal
PY  - 2026
DA  - 2026/11/09
JO  - Clinical case reports
DO  - 10.1002/ccr3.73911
UR  - https://europepmc.org/article/MED/43011232
AB  - In a 14-year-old with antiphospholipid syndrome (APS) and lupus anticoagulant, improper switching from warfarin and low-dose aspirin to rivaroxaban led to life-threatening recurrent thrombosis, pulmonary embolism, and pulmonary hypertension. Prompt return to standard anticoagulation plus immunosuppression stabilized the condition. This case underscores that DOACs are contraindicated in high-risk APS.
SN  - 2050-0904
ER  -