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Peer-reviewedCC BY-NC-NDActa medica Philippina

Conjunctival Squamous Cell Carcinoma Masquerading as a Post-traumatic Subconjunctival Mass: A Case Report.

  1. 1Department of Ophthalmology and Visual Sciences, Philippine General Hospital, University of the Philippines Manila, Manila, Philippines.
  2. 2Eye Institute, St. Luke's Medical Center, Quezon City, Philippines.

Abstract

Conjunctival squamous cell carcinoma (SCC) is the most common malignant tumor of the ocular surface, though it remains relatively rare. It typically occurs within the interpalpebral fissure, predominantly affecting elderly males with significant ultraviolet (UV) light exposure. We present the case of an elderly male in his 60s who developed a subconjunctival mass 1 year following ocular trauma. Initially, the subconjunctival mass was presumed to be of infectious origin, leading to treatment with topical antibiotics and excision. However, the mass recurred, prompting further investigation. Histopathologic analysis of the excised tissue revealed squamous cell carcinoma. Subsequently, the patient was treated with topical 5-fluorouracil, resulting in complete regression of the lesion. This case highlights the importance of considering neoplastic etiologies, even in the presence of an atypical clinical presentation and history. The delayed onset and unusual anatomic location of the mass, following trauma, underscores the need for vigilance in the differential diagnosis of conjunctival lesions, especially in patients with known risk factors such as advanced age and UV light exposure.

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BibTeX
@article{acopiado2026conjunctival,
  title = {{Conjunctival Squamous Cell Carcinoma Masquerading as a Post-traumatic Subconjunctival Mass: A Case Report.}},
  author = {Oscar A Acopiado and George Michael N Sosuan and Ruben Lim Bon Siong},
  journal = {Acta medica Philippina},
  year = {2026},
  month = sep,
  doi = {10.47895/amp.v60i17.13423},
  url = {https://europepmc.org/article/MED/42952885},
  note = {CC BY-NC-ND},
}
RIS
TY  - JOUR
TI  - Conjunctival Squamous Cell Carcinoma Masquerading as a Post-traumatic Subconjunctival Mass: A Case Report.
AU  - Oscar A Acopiado
AU  - George Michael N Sosuan
AU  - Ruben Lim Bon Siong
PY  - 2026
DA  - 2026/09/15
JO  - Acta medica Philippina
DO  - 10.47895/amp.v60i17.13423
UR  - https://europepmc.org/article/MED/42952885
AB  - Conjunctival squamous cell carcinoma (SCC) is the most common malignant tumor of the ocular surface, though it remains relatively rare. It typically occurs within the interpalpebral fissure, predominantly affecting elderly males with significant ultraviolet (UV) light exposure. We present the case of an elderly male in his 60s who developed a subconjunctival mass 1 year following ocular trauma. Initially, the subconjunctival mass was presumed to be of infectious origin, leading to treatment with topical antibiotics and excision. However, the mass recurred, prompting further investigation. Histopathologic analysis of the excised tissue revealed squamous cell carcinoma. Subsequently, the patient was treated with topical 5-fluorouracil, resulting in complete regression of the lesion. This case highlights the importance of considering neoplastic etiologies, even in the presence of an atypical clinical presentation and history. The delayed onset and unusual anatomic location of the mass, following trauma, underscores the need for vigilance in the differential diagnosis of conjunctival lesions, especially in patients with known risk factors such as advanced age and UV light exposure.
SN  - 0001-6071
SN  - 2094-9278
ER  -