Peer-reviewedCC BY-NC-SAIndian journal of urology : IJU : journal of the Urological Society of India
Bilateral complete staghorn uric acid calculi successfully managed with oral chemolysis.
- 1Department of Urology and Kidney Transplant, Zydus Hospital, Vadodara, Gujarat, India.
- 2Department of Urology, Icahn School of Medicine at Mount Sinai, NY, USA.
Abstract
Staghorn stones are typically managed surgically due to their size, complexity, and infection risk. Uric acid stones are an exception. Prior reports of medical dissolution have been limited to small stones (<20 mm). Here, we report a case in which large uric acid staghorn stones were successfully cleared with medical therapy. A 43-year-old male presented with bilateral uric acid staghorn calculi measuring 42 mm (27,155 mm³) and 29 mm (11,562 mm³) and obstructing left ureteral stones that required ureteroscopy. Treatment with febuxostat and potassium citrate resulted in dissolution of the staghorn stones after 15 weeks of therapy, on computed tomography imaging.
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BibTeX
@article{thummar2026bilateral,
title = {{Bilateral complete staghorn uric acid calculi successfully managed with oral chemolysis.}},
author = {Haresh Thummar and Veda Malhotra and Mantu Gupta},
journal = {Indian journal of urology : IJU : journal of the Urological Society of India},
year = {2026},
month = sep,
doi = {10.4103/iju.iju_331_26},
url = {https://europepmc.org/article/MED/42910088},
note = {CC BY-NC-SA},
}
RIS
TY - JOUR
TI - Bilateral complete staghorn uric acid calculi successfully managed with oral chemolysis.
AU - Haresh Thummar
AU - Veda Malhotra
AU - Mantu Gupta
PY - 2026
DA - 2026/09/29
JO - Indian journal of urology : IJU : journal of the Urological Society of India
DO - 10.4103/iju.iju_331_26
UR - https://europepmc.org/article/MED/42910088
AB - Staghorn stones are typically managed surgically due to their size, complexity, and infection risk. Uric acid stones are an exception. Prior reports of medical dissolution have been limited to small stones (<20 mm). Here, we report a case in which large uric acid staghorn stones were successfully cleared with medical therapy. A 43-year-old male presented with bilateral uric acid staghorn calculi measuring 42 mm (27,155 mm³) and 29 mm (11,562 mm³) and obstructing left ureteral stones that required ureteroscopy. Treatment with febuxostat and potassium citrate resulted in dissolution of the staghorn stones after 15 weeks of therapy, on computed tomography imaging.
SN - 0970-1591
SN - 1998-3824
ER -