Comparison of clinical outcomes after 25-gauge vitrectomy with and without uncomplicated cataract surgery for idiopathic epiretinal membrane.
4 affiliations
- 1Department of Ophthalmology, Central Theater Command General Hospital of PLA (Hubei Provincial Clinical Medical Research Center for Laser Fundus Diseases), 627# Wuluo Road, Wuhan, Hubei, 430070, China.
- 2Department of Ophthalmology, Central Theater Command General Hospital of PLA (Hubei Provincial Clinical Medical Research Center for Laser Fundus Diseases), 627# Wuluo Road, Wuhan, Hubei, 430070, China. [email protected].
- 3Wuhan University of Science and Technology, Wuhan, China. [email protected].
- 4Southern Medical University, Guangzhou, China. [email protected].
Abstract
Purpose
To compare the functional and anatomical outcomes of 25-gauge pars plana vitrectomy (PPV) with and without uncomplicated cataract surgery for idiopathic epiretinal membrane (IERM) in phakic eyes.Methods
In this retrospective clinical study, we recruited 85 phakic eyes with IERM and distributed in two groups: pars plana vitrectomy group (PPV group) and PPV combined with uncomplicated cataract surgery group (Combined group). Examinations were at baseline, 1 month, 3 months, 6 months and 12 months after each surgery. Primary outcome was the metamorphopsia; secondary outcomes were the best-corrected visual acuity (BCVA) and central macular thickness (CMT).Results
The vertical and horizontal metamorphopsia scores decreased significantly in both groups at 12 months after surgery. There was no statistical difference between the two groups in vertical and horizontal metamorphopsia reduction at 12 months (p = 0.513 and 0.522 respectively). The mean BCVA of both groups improved significantly at 12 months after surgery (p = 0.003 for the PPV group, p < 0.001 for the Combined group), the final BCVA in the Combined group was better than that in the PPV group (p = 0.011). The mean CMT also decreased significantly at 12 months after surgery in both groups (p < 0.001 for both groups), there was no statistical difference between the two groups in CMT at 12 months (p = 0.160).Conclusions
Combined vitrectomy with uncomplicated cataract surgery may potentially be as effective as vitrectomy alone with respect to metamorphopsia and anatomical outcomes for IERM patients. However, the BCVA recovery was better in the Combined group.
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BibTeX
@article{zeng2026comparison,
title = {{Comparison of clinical outcomes after 25-gauge vitrectomy with and without uncomplicated cataract surgery for idiopathic epiretinal membrane.}},
author = {Miao Zeng and Xiao Chen and Yin Yan and Li Zhu and Zhijian Huang},
journal = {BMC ophthalmology},
year = {2026},
month = aug,
doi = {10.1186/s12886-026-05157-1},
url = {https://europepmc.org/article/MED/42963756},
note = {CC BY-NC-ND},
}
RIS
TY - JOUR
TI - Comparison of clinical outcomes after 25-gauge vitrectomy with and without uncomplicated cataract surgery for idiopathic epiretinal membrane.
AU - Miao Zeng
AU - Xiao Chen
AU - Yin Yan
AU - Li Zhu
AU - Zhijian Huang
PY - 2026
DA - 2026/08/04
JO - BMC ophthalmology
DO - 10.1186/s12886-026-05157-1
UR - https://europepmc.org/article/MED/42963756
AB - Purpose To compare the functional and anatomical outcomes of 25-gauge pars plana vitrectomy (PPV) with and without uncomplicated cataract surgery for idiopathic epiretinal membrane (IERM) in phakic eyes.Methods In this retrospective clinical study, we recruited 85 phakic eyes with IERM and distributed in two groups: pars plana vitrectomy group (PPV group) and PPV combined with uncomplicated cataract surgery group (Combined group). Examinations were at baseline, 1 month, 3 months, 6 months and 12 months after each surgery. Primary outcome was the metamorphopsia; secondary outcomes were the best-corrected visual acuity (BCVA) and central macular thickness (CMT).Results The vertical and horizontal metamorphopsia scores decreased significantly in both groups at 12 months after surgery. There was no statistical difference between the two groups in vertical and horizontal metamorphopsia reduction at 12 months (p = 0.513 and 0.522 respectively). The mean BCVA of both groups improved significantly at 12 months after surgery (p = 0.003 for the PPV group, p < 0.001 for the Combined group), the final BCVA in the Combined group was better than that in the PPV group (p = 0.011). The mean CMT also decreased significantly at 12 months after surgery in both groups (p < 0.001 for both groups), there was no statistical difference between the two groups in CMT at 12 months (p = 0.160).Conclusions Combined vitrectomy with uncomplicated cataract surgery may potentially be as effective as vitrectomy alone with respect to metamorphopsia and anatomical outcomes for IERM patients. However, the BCVA recovery was better in the Combined group.
SN - 1471-2415
ER -