Clinical Characteristics of Cerebral Venous Thrombosis: A Descriptive Study from Minia University Hospital
5 affiliations
- 1Neurology department , faculty of medicine , minia universoty
- 2Department of Neurology and Psychiatry, Minia University, Minia, Egypt
- 3Neurology Department, Faculty of Medicine, Minia University, Minia, Egypt
- 4neurology department , faculty of medicine , Minia university ,Minia city , Egypt
- 5Neurology and psychiatry department, minia university hospital
Abstract
Background: Cerebral venous thrombosis (CVT) is an uncommon cerebrovascular disorder with variable clinical manifestations and multiple predisposing factors. Descriptive data from tertiary-care centers can help characterize its clinical and radiological spectrum. Objective: To describe the clinical manifestations, laboratory findings, and neuroimaging findings in patients with CVT treated at Minia University Hospital. Methods: A descriptive observational study was conducted on 40 patients with CVT. Clinical manifestations, laboratory investigations, and brain computed tomography (CT), magnetic resonance imaging (MRI), and magnetic resonance venography (MRV) findings were evaluated. Data were summarized using frequencies, percentages, means, standard deviations, and medians with ranges. Results: Headache was the most common presenting symptom, occurring in 34 patients (85.0%), followed by seizures in 24 (60.0%), papilledema in 20 (50.0%), and weakness in 16 (40.0%). Laboratory investigations were generally unremarkable. Antiphospholipid antibody syndrome was detected in 4 patients (10.0%), while systemic lupus erythematosus was found in 2 (5.0%). CT and MRI were normal in 20 patients (50.0%); venous infarction was detected in 8 (20.0%) and hemorrhagic infarction in 12 (30.0%). MRV showed transverse sinus thrombosis in 22 patients (55.0%), superior sagittal sinus thrombosis in 12 (30.0%), and deep venous system thrombosis in 6 (15.0%). Conclusion: Headache, seizures, and signs of raised intracranial pressure were the predominant clinical features. Transverse sinus was the most commonly affected sinus, while CT and MRI were normal in half of the patients.
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BibTeX
@article{mahmoud2026clinical,
title = {{Clinical Characteristics of Cerebral Venous Thrombosis: A Descriptive Study from Minia University Hospital}},
author = {Enas Mahmoud and mohamed yahia and Muhammad Ismail and Rasha Saleh and Yehia Yehia},
journal = {Minia Journal of Medical Research},
year = {2026},
month = oct,
doi = {10.21608/mjmr.2026.537052.2406},
url = {https://doi.org/10.21608/mjmr.2026.537052.2406},
note = {CC BY},
}
RIS
TY - JOUR
TI - Clinical Characteristics of Cerebral Venous Thrombosis: A Descriptive Study from Minia University Hospital
AU - Enas Mahmoud
AU - mohamed yahia
AU - Muhammad Ismail
AU - Rasha Saleh
AU - Yehia Yehia
PY - 2026
DA - 2026/10/25
JO - Minia Journal of Medical Research
DO - 10.21608/mjmr.2026.537052.2406
UR - https://doi.org/10.21608/mjmr.2026.537052.2406
AB - Background: Cerebral venous thrombosis (CVT) is an uncommon cerebrovascular disorder with variable clinical manifestations and multiple predisposing factors. Descriptive data from tertiary-care centers can help characterize its clinical and radiological spectrum. Objective: To describe the clinical manifestations, laboratory findings, and neuroimaging findings in patients with CVT treated at Minia University Hospital. Methods: A descriptive observational study was conducted on 40 patients with CVT. Clinical manifestations, laboratory investigations, and brain computed tomography (CT), magnetic resonance imaging (MRI), and magnetic resonance venography (MRV) findings were evaluated. Data were summarized using frequencies, percentages, means, standard deviations, and medians with ranges. Results: Headache was the most common presenting symptom, occurring in 34 patients (85.0%), followed by seizures in 24 (60.0%), papilledema in 20 (50.0%), and weakness in 16 (40.0%). Laboratory investigations were generally unremarkable. Antiphospholipid antibody syndrome was detected in 4 patients (10.0%), while systemic lupus erythematosus was found in 2 (5.0%). CT and MRI were normal in 20 patients (50.0%); venous infarction was detected in 8 (20.0%) and hemorrhagic infarction in 12 (30.0%). MRV showed transverse sinus thrombosis in 22 patients (55.0%), superior sagittal sinus thrombosis in 12 (30.0%), and deep venous system thrombosis in 6 (15.0%). Conclusion: Headache, seizures, and signs of raised intracranial pressure were the predominant clinical features. Transverse sinus was the most commonly affected sinus, while CT and MRI were normal in half of the patients.
SN - 2682-4558
ER -