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Peer-reviewedCC BY 4.0Nature Communications

Energy-guided combinatorial co-optimization of antibody affinity and stability

  • Ariel Tennenhouse
  • Adva Mechaly
  • Tony Pham
  • Robert J. Oldham
  • Jake Y. Henry
  • Dorry X. Zhao
  • Thomas M. Moon
  • Isabel G. Elliott
  • Omri Porat
  • Jinny Kim
  • Yael Fridmann Sirkis
  • Sveta Gaiduk
10 more authors
  • Itay Talpir
  • Jamie Bird
  • Christopher Domalewski
  • Pei-Hsuan Chu
  • Andrew B. Dippel
  • Rebecca Croasdale-Wood
  • Daniel Christ
  • Gilad Kaplan
  • Mark S. Cragg
  • Sarel J. Fleishman
Open at sourceDOICite

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Cite

BibTeXRIS
BibTeX
@article{tennenhouse2026energyguided,
  title = {{Energy-guided combinatorial co-optimization of antibody affinity and stability}},
  author = {Ariel Tennenhouse and Adva Mechaly and Tony Pham and Robert J. Oldham and Jake Y. Henry and Dorry X. Zhao and Thomas M. Moon and Isabel G. Elliott and Omri Porat and Jinny Kim and Yael Fridmann Sirkis and Sveta Gaiduk and Itay Talpir and Jamie Bird and Christopher Domalewski and Pei-Hsuan Chu and Andrew B. Dippel and Rebecca Croasdale-Wood and Daniel Christ and Gilad Kaplan and Mark S. Cragg and Sarel J. Fleishman},
  journal = {Nature Communications},
  year = {2026},
  month = nov,
  doi = {10.1038/s41467-026-78946-3},
  url = {https://www.nature.com/articles/s41467-026-78946-3},
  note = {CC BY 4.0},
}
RIS
TY  - JOUR
TI  - Energy-guided combinatorial co-optimization of antibody affinity and stability
AU  - Ariel Tennenhouse
AU  - Adva Mechaly
AU  - Tony Pham
AU  - Robert J. Oldham
AU  - Jake Y. Henry
AU  - Dorry X. Zhao
AU  - Thomas M. Moon
AU  - Isabel G. Elliott
AU  - Omri Porat
AU  - Jinny Kim
AU  - Yael Fridmann Sirkis
AU  - Sveta Gaiduk
AU  - Itay Talpir
AU  - Jamie Bird
AU  - Christopher Domalewski
AU  - Pei-Hsuan Chu
AU  - Andrew B. Dippel
AU  - Rebecca Croasdale-Wood
AU  - Daniel Christ
AU  - Gilad Kaplan
AU  - Mark S. Cragg
AU  - Sarel J. Fleishman
PY  - 2026
DA  - 2026/11/05
JO  - Nature Communications
DO  - 10.1038/s41467-026-78946-3
UR  - https://www.nature.com/articles/s41467-026-78946-3
SN  - 2041-1723
ER  -