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Peer-reviewedCC BY-NC-NDInternal Medicine

Home Intravenous Heparin Therapy via a Central Venous Port for Recurrent Cancer-associated Stroke Requiring Repeat Mechanical Thrombectomy

Abstract

Cancer-associated stroke (CAS) presents significant challenges regarding secondary prevention. A 48-year-old woman with pancreatic cancer experienced two episodes of large-vessel occlusion stroke was treated by mechanical thrombectomy. Subcutaneous heparin was discontinued owing to skin reactions, and recurrence occurred despite the use of a direct oral anticoagulant. As an alternative, intravenous heparin was initiated at home via a chemotherapy port, using a portable infusion pump. This individualized approach was implemented without any major complications, and it may represent a practical option for patients with CAS who are either intolerant or refractory to conventional therapies.

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BibTeX
@article{kameda2026home,
  title = {{Home Intravenous Heparin Therapy via a Central Venous Port for Recurrent Cancer-associated Stroke Requiring Repeat Mechanical Thrombectomy}},
  author = {Tomoaki Kameda and Shunichi Okada and Risa Suzuki and Takahito Nishihira and Akito Mori and Yasuhiro Hidaka and Tadataka Kawakami and Shigeru Fujimoto},
  journal = {Internal Medicine},
  year = {2026},
  month = jul,
  doi = {10.2169/internalmedicine.6405-25},
  url = {https://www.jstage.jst.go.jp/article/internalmedicine/65/14/65_6405-25/_article},
  note = {CC BY-NC-ND},
}
RIS
TY  - JOUR
TI  - Home Intravenous Heparin Therapy via a Central Venous Port for Recurrent Cancer-associated Stroke Requiring Repeat Mechanical Thrombectomy
AU  - Tomoaki Kameda
AU  - Shunichi Okada
AU  - Risa Suzuki
AU  - Takahito Nishihira
AU  - Akito Mori
AU  - Yasuhiro Hidaka
AU  - Tadataka Kawakami
AU  - Shigeru Fujimoto
PY  - 2026
DA  - 2026/07/15
JO  - Internal Medicine
DO  - 10.2169/internalmedicine.6405-25
UR  - https://www.jstage.jst.go.jp/article/internalmedicine/65/14/65_6405-25/_article
AB  - Cancer-associated stroke (CAS) presents significant challenges regarding secondary prevention. A 48-year-old woman with pancreatic cancer experienced two episodes of large-vessel occlusion stroke was treated by mechanical thrombectomy. Subcutaneous heparin was discontinued owing to skin reactions, and recurrence occurred despite the use of a direct oral anticoagulant. As an alternative, intravenous heparin was initiated at home via a chemotherapy port, using a portable infusion pump. This individualized approach was implemented without any major complications, and it may represent a practical option for patients with CAS who are either intolerant or refractory to conventional therapies.
SN  - 1349-7235
SN  - 0918-2918
ER  -