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Peer-reviewedCC BY-NC-NDOncology letters

Drug-eluting bead transarterial chemoembolization with immunotherapy and targeted therapy for advanced clear cell renal cell carcinoma: A case report.

  1. 1Department of Oncology, The Affiliated Hospital of Yanbian University (Yanbian Hospital), Yanji, Jilin 133000, P.R. China.

Abstract

Abdominal wall metastasis is a rare metastatic pattern of clear cell renal cell carcinoma and is typically associated with advanced disease and poor prognosis. Due to its unique anatomical location and complex vascular supply, conventional systemic therapies have limited efficacy in controlling these metastases, and surgical resection is often challenging due to the deep-seated location of the tumor and its proximity to vital structures. Drug-eluting bead transarterial chemoembolization (DEB-TACE) is a promising locoregional therapeutic option for patients with refractory metastases. The present case report described a multimodal treatment strategy centered on DEB-TACE combined with an immune checkpoint inhibitor and a tyrosine kinase inhibitor in the treatment of this rare clinical scenario.

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BibTeX
@article{gao2026drugeluting,
  title = {{Drug-eluting bead transarterial chemoembolization with immunotherapy and targeted therapy for advanced clear cell renal cell carcinoma: A case report.}},
  author = {Yin Gao and Qiang Xu and Dongxu Kang and Longzhen Piao},
  journal = {Oncology letters},
  year = {2026},
  month = oct,
  doi = {10.3892/ol.2026.15899},
  url = {https://europepmc.org/article/MED/42924150},
  note = {CC BY-NC-ND},
}
RIS
TY  - JOUR
TI  - Drug-eluting bead transarterial chemoembolization with immunotherapy and targeted therapy for advanced clear cell renal cell carcinoma: A case report.
AU  - Yin Gao
AU  - Qiang Xu
AU  - Dongxu Kang
AU  - Longzhen Piao
PY  - 2026
DA  - 2026/10/08
JO  - Oncology letters
DO  - 10.3892/ol.2026.15899
UR  - https://europepmc.org/article/MED/42924150
AB  - Abdominal wall metastasis is a rare metastatic pattern of clear cell renal cell carcinoma and is typically associated with advanced disease and poor prognosis. Due to its unique anatomical location and complex vascular supply, conventional systemic therapies have limited efficacy in controlling these metastases, and surgical resection is often challenging due to the deep-seated location of the tumor and its proximity to vital structures. Drug-eluting bead transarterial chemoembolization (DEB-TACE) is a promising locoregional therapeutic option for patients with refractory metastases. The present case report described a multimodal treatment strategy centered on DEB-TACE combined with an immune checkpoint inhibitor and a tyrosine kinase inhibitor in the treatment of this rare clinical scenario.
SN  - 1792-1074
SN  - 1792-1082
ER  -