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PreprintCC BY-NC-NDmedRxiv

Mental health before, during, and after COVID-19 (through 2025) in boys, girls, and gender-diverse youth

  1. 1Department of Healthcare and Social Welfare, Finnish Institute for Health and Welfare

Abstract

BackgroundAdolescent mental health after the COVID-19 pandemic has been a major public health concern. Studies covering the post-pandemic period remain scarce and rarely include gender-diverse youth. We examined trends in mental health among cisgender, transgender, and nonbinary youth during the pandemic and through 2025.

MethodsParticipants (N=636,201) were adolescents in grades 8-11 from the Finnish School Health Promotion study between 2019 and 2025, a repeated cross-sectional classroom survey.

Validated questionnaires were used to assess clinical levels of depressive, generalized anxiety and social anxiety symptoms, as well as mental well-being.

ResultsIn 2025 there were 81,145 (48.6%) cisgender girls, 1137 (0.7%) transgender boys, 78,898 (47.2%) cisgender boys, 449 (0.3%) transgender girls, and 4658 (2.8%) nonbinary youth. Clinically significant depressive and generalized anxiety symptoms remained more prevalent in 2025 (reference) compared with pre-pandemic levels across all groups (ORs for 2019, 0.48-0.86; p<0.01). Compared with other groups, symptoms were most prevalent among transgender boys and nonbinary youth. Among cisgender youth, generalized anxiety symptoms increased across the post-pandemic period (ORs for 2021 and 2023, 0.81-0.95; p<0.0001). Nonbinary youth were the only group to show a recovery pattern in depressive, generalized anxiety, and social anxiety symptoms (ORs for 2021, 1.36-1.52; p<0.0001) and demonstrated improved mental well-being after the pandemic (beta for 2021, -0.68; p<0.0001).

ConclusionsThe results indicate that the elevated levels of mental health problems among adolescents associated with the COVID-19 pandemic have not subsided. They also reveal persistent disparities by gender identity and call for targeted policy action.

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BibTeX
@misc{kiviruusu2026mental,
  title = {{Mental health before, during, and after COVID-19 (through 2025) in boys, girls, and gender-diverse youth}},
  author = {O. Kiviruusu and S. Therman and J. Lehtonen and E. Ystrom and A. Butwicka and T. Halldorsdottir and H. Ask and J. Suvisaari},
  howpublished = {medRxiv},
  year = {2026},
  month = sep,
  doi = {10.64898/2026.09.06.26362161},
  url = {https://www.medrxiv.org/content/10.64898/2026.09.06.26362161v1},
  note = {CC BY-NC-ND},
}
RIS
TY  - UNPB
TI  - Mental health before, during, and after COVID-19 (through 2025) in boys, girls, and gender-diverse youth
AU  - O. Kiviruusu
AU  - S. Therman
AU  - J. Lehtonen
AU  - E. Ystrom
AU  - A. Butwicka
AU  - T. Halldorsdottir
AU  - H. Ask
AU  - J. Suvisaari
PY  - 2026
DA  - 2026/09/06
PB  - medRxiv
DO  - 10.64898/2026.09.06.26362161
UR  - https://www.medrxiv.org/content/10.64898/2026.09.06.26362161v1
AB  - BackgroundAdolescent mental health after the COVID-19 pandemic has been a major public health concern. Studies covering the post-pandemic period remain scarce and rarely include gender-diverse youth. We examined trends in mental health among cisgender, transgender, and nonbinary youth during the pandemic and through 2025.  MethodsParticipants (N=636,201) were adolescents in grades 8-11 from the Finnish School Health Promotion study between 2019 and 2025, a repeated cross-sectional classroom survey.  Validated questionnaires were used to assess clinical levels of depressive, generalized anxiety and social anxiety symptoms, as well as mental well-being.  ResultsIn 2025 there were 81,145 (48.6%) cisgender girls, 1137 (0.7%) transgender boys, 78,898 (47.2%) cisgender boys, 449 (0.3%) transgender girls, and 4658 (2.8%) nonbinary youth. Clinically significant depressive and generalized anxiety symptoms remained more prevalent in 2025 (reference) compared with pre-pandemic levels across all groups (ORs for 2019, 0.48-0.86; p<0.01). Compared with other groups, symptoms were most prevalent among transgender boys and nonbinary youth. Among cisgender youth, generalized anxiety symptoms increased across the post-pandemic period (ORs for 2021 and 2023, 0.81-0.95; p<0.0001). Nonbinary youth were the only group to show a recovery pattern in depressive, generalized anxiety, and social anxiety symptoms (ORs for 2021, 1.36-1.52; p<0.0001) and demonstrated improved mental well-being after the pandemic (beta for 2021, -0.68; p<0.0001).  ConclusionsThe results indicate that the elevated levels of mental health problems among adolescents associated with the COVID-19 pandemic have not subsided. They also reveal persistent disparities by gender identity and call for targeted policy action.
ER  -