Structure–Function Relationships in Galactomannan Starch Films for Fast-Dissolving Applications: Effects on Physicochemical and Mechanical Properties
Abstract
Orally disintegrating films (ODFs) have attracted increasing attention because of their rapid disintegration and ease of administration. In this study, galactomannan–starch biopolymer films were developed as fast-dissolving oral film matrices using galactomannan extracted from Caesalpinia pulcherrima combined with corn and arrowroot (Maranta arundinacea) starches at different proportions. The effect of polymer composition on structure–function relationships was systematically investigated, with emphasis on how intermolecular interactions influence the physicochemical and mechanical properties of the films. Starch incorporation significantly affected polymer-network organization, leading to changes in rheological behavior, morphology, and macroscopic performance. Mechanical properties were strongly dependent on starch type: corn starch promoted greater flexibility, whereas arrowroot starch increased rigidity, likely because of differences in amylose content. The films exhibited homogeneous morphology, high transparency, and surface pH values close to neutrality. Water affinity and disintegration behavior were directly influenced by polymer composition, highlighting the role of polymer–polymer interactions in controlling hydration and the structural stability of the developed film matrices. Spectroscopic analysis suggested the presence of intermolecular interactions, particularly hydrogen bonding, which contributed to the modulation of film properties. Among the evaluated formulations, the system containing 75% galactomannan and 25% corn starch exhibited a balanced combination of mechanical strength, flexibility, and rapid disintegration. These findings demonstrate that galactomannan–starch blends are promising materials for ODF applications and provide insights into tailoring structure–function relationships in sustainable biopolymer systems.
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BibTeX
@article{sampaio2026structurefunction,
title = {{Structure–Function Relationships in Galactomannan Starch Films for Fast-Dissolving Applications: Effects on Physicochemical and Mechanical Properties}},
author = {Lorena M. F. Sampaio and Matheus Oliveira and Venícios G. Sombra and Judith P.A. Feitosa and Nayanne dos S. Ferreira and Maria Do S. R. Bastos and Sara Marciano and Diego Lomonaco and Amélia Lima and Lara Mota Soares and Crisiana de A. Nobre and Kaliana Eça and Thomas Karbowiak and Luciana de S. Oliveira},
journal = {ACS Omega},
year = {2026},
month = aug,
doi = {10.1021/acsomega.6c04905},
url = {https://institut-agro-dijon.hal.science/hal-05745699v1},
note = {CC BY 4.0},
}
RIS
TY - JOUR
TI - Structure–Function Relationships in Galactomannan Starch Films for Fast-Dissolving Applications: Effects on Physicochemical and Mechanical Properties
AU - Lorena M. F. Sampaio
AU - Matheus Oliveira
AU - Venícios G. Sombra
AU - Judith P.A. Feitosa
AU - Nayanne dos S. Ferreira
AU - Maria Do S. R. Bastos
AU - Sara Marciano
AU - Diego Lomonaco
AU - Amélia Lima
AU - Lara Mota Soares
AU - Crisiana de A. Nobre
AU - Kaliana Eça
AU - Thomas Karbowiak
AU - Luciana de S. Oliveira
PY - 2026
DA - 2026/08/28
JO - ACS Omega
DO - 10.1021/acsomega.6c04905
UR - https://institut-agro-dijon.hal.science/hal-05745699v1
AB - Orally disintegrating films (ODFs) have attracted increasing attention because of their rapid disintegration and ease of administration. In this study, galactomannan–starch biopolymer films were developed as fast-dissolving oral film matrices using galactomannan extracted from Caesalpinia pulcherrima combined with corn and arrowroot (Maranta arundinacea) starches at different proportions. The effect of polymer composition on structure–function relationships was systematically investigated, with emphasis on how intermolecular interactions influence the physicochemical and mechanical properties of the films. Starch incorporation significantly affected polymer-network organization, leading to changes in rheological behavior, morphology, and macroscopic performance. Mechanical properties were strongly dependent on starch type: corn starch promoted greater flexibility, whereas arrowroot starch increased rigidity, likely because of differences in amylose content. The films exhibited homogeneous morphology, high transparency, and surface pH values close to neutrality. Water affinity and disintegration behavior were directly influenced by polymer composition, highlighting the role of polymer–polymer interactions in controlling hydration and the structural stability of the developed film matrices. Spectroscopic analysis suggested the presence of intermolecular interactions, particularly hydrogen bonding, which contributed to the modulation of film properties. Among the evaluated formulations, the system containing 75% galactomannan and 25% corn starch exhibited a balanced combination of mechanical strength, flexibility, and rapid disintegration. These findings demonstrate that galactomannan–starch blends are promising materials for ODF applications and provide insights into tailoring structure–function relationships in sustainable biopolymer systems.
SN - 2470-1343
ER -