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Peer-reviewedCC BYScience advances

Integrative multi-omics reveals CUL4B as a modulator of macrophage pyroptosis and innate defense against Staphylococcus aureus

  • Fatemeh Askarian1
  • Daniel Sun1
  • Jasmine Tat2
  • James T. Sorrentino2
  • Armin Kousha1
  • Consuelo Sauceda3
  • Siri Yendluri1
  • Yu Yan4
  • Ka Pui Sharon Yau1
  • Helen Masson2
  • Jacob Wozniak3,5
  • Kristin Pettersen6
17 more authors
  • Natalie Chavarria1
  • Ella McLaren1
  • Hunter Gage1
  • Alexandria Hoffman1
  • Stanley Davis1
  • Chih-Ming Tsai1,7
  • Jonathan Monk2
  • Angela Meier8
  • George Sakoulas1
  • Tom Eirik Mollnes6,9,10
  • Gustav Vaaje-Kolstad11
  • Ingrid Cornax1
  • Pengbo Zhou4
  • Mona Johannessen12
  • David J. Gonzalez3
  • Nathan E. Lewis1,2,13
  • Victor Nizet1,3
13 affiliations
  1. 1Department of Pediatrics, University of California San Diego, School of Medicine, La Jolla, CA, USA.
  2. 2Department of Bioengineering, University of California San Diego, School of Medicine, La Jolla, CA, USA.
  3. 3Skaggs School of Pharmacy and Pharmaceutical Sciences, UC San Diego, La Jolla, CA, USA.
  4. 4Department of Pathology and Laboratory Medicine, Weill Medical College and Graduate School of Medical Sciences of Cornell University, New York, NY, USA.
  5. 5Department of Pharmacology, University of California, San Diego, La Jolla, CA, USA.
  6. 6Research Laboratory, Nordland Hospital, Bodø, Norway.
  7. 7Paul G. Allen School for Global Health, Washington State University, Pullman, WA 99164.
  8. 8Department of Anesthesiology, Division of Critical Care, University of California San Diego, La Jolla, CA, USA.
  9. 9Department of Immunology, Oslo University, Oslo, Norway.
  10. 10Department of Immunology, Oslo University Hospital, Oslo, Norway.
  11. 11Faculty of Chemistry, Biotechnology and Food Science, Norwegian University of Life Sciences, Ås, Norway.
  12. 12Department of Medical Biology, Faculty of Health Sciences, UiT–The Arctic University of Norway, Tromsø, Norway.
  13. 13Center for Molecular Medicine, Complex Carbohydrate Research Center, and Department of Biochemistry and Molecular Biology, University of Georgia, Athens, GA, USA.
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Cite

BibTeXRIS
BibTeX
@article{askarian2026integrative,
  title = {{Integrative multi-omics reveals CUL4B as a modulator of macrophage pyroptosis and innate defense against Staphylococcus aureus}},
  author = {Fatemeh Askarian and Daniel Sun and Jasmine Tat and James T. Sorrentino and Armin Kousha and Consuelo Sauceda and Siri Yendluri and Yu Yan and Ka Pui Sharon Yau and Helen Masson and Jacob Wozniak and Kristin Pettersen and Natalie Chavarria and Ella McLaren and Hunter Gage and Alexandria Hoffman and Stanley Davis and Chih-Ming Tsai and Jonathan Monk and Angela Meier and George Sakoulas and Tom Eirik Mollnes and Gustav Vaaje-Kolstad and Ingrid Cornax and Pengbo Zhou and Mona Johannessen and David J. Gonzalez and Nathan E. Lewis and Victor Nizet},
  journal = {Science advances},
  year = {2026},
  month = oct,
  doi = {10.1126/sciadv.aeh4023},
  url = {https://europepmc.org/article/PMC/PMC13665969},
  note = {CC BY},
}
RIS
TY  - JOUR
TI  - Integrative multi-omics reveals CUL4B as a modulator of macrophage pyroptosis and innate defense against Staphylococcus aureus
AU  - Fatemeh Askarian
AU  - Daniel Sun
AU  - Jasmine Tat
AU  - James T. Sorrentino
AU  - Armin Kousha
AU  - Consuelo Sauceda
AU  - Siri Yendluri
AU  - Yu Yan
AU  - Ka Pui Sharon Yau
AU  - Helen Masson
AU  - Jacob Wozniak
AU  - Kristin Pettersen
AU  - Natalie Chavarria
AU  - Ella McLaren
AU  - Hunter Gage
AU  - Alexandria Hoffman
AU  - Stanley Davis
AU  - Chih-Ming Tsai
AU  - Jonathan Monk
AU  - Angela Meier
AU  - George Sakoulas
AU  - Tom Eirik Mollnes
AU  - Gustav Vaaje-Kolstad
AU  - Ingrid Cornax
AU  - Pengbo Zhou
AU  - Mona Johannessen
AU  - David J. Gonzalez
AU  - Nathan E. Lewis
AU  - Victor Nizet
PY  - 2026
DA  - 2026/10/16
JO  - Science advances
DO  - 10.1126/sciadv.aeh4023
UR  - https://europepmc.org/article/PMC/PMC13665969
SN  - 2375-2548
ER  -