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PreprintarXiv licencearXiv

How Wrong Can a Rank-Based Sample-Size Calculation Be? A Sharp Bound of 16/9 for Ordinal Outcomes

Abstract

Rank-based tests need no distributional assumptions to be valid, but the sample size they require does depend on the shapes of the two outcome distributions, which are unknown at the design stage. Standard practice substitutes a variance calibrated under the null. We ask how wrong that substitution can be. Writing Π for the ratio of the true asymptotic variance of the estimated relative effect to the substituted one, we prove that under balanced allocation Π≤ 16θ(1−θ)/{2+θ(1−θ)} ≤ 16/9 for all ordinal distributions in any number of categories: within the first-order asymptotic calculation the required sample size can exceed the calculated one by at most 77.8%, and an explicit two-point family attains the bound at every effect size. The effect-specific envelope, not the constant, is the operative quantity for a design: the ceiling falls to $1.63$ at θ=0.65 and $1.37$ at θ=0.75, so a trial powered for a larger effect is correspondingly less exposed. The proof is elementary. In five extracted trial comparisons and 4,711 generated alternatives the realized cost stays within a few percent, because the extremal configuration is one that shift-type treatment mechanisms do not produce. These facts are complementary, and fix how the bound should be used: it is a design sensitivity certificate, not an inflation factor. A protocol can report the conventional sample size alongside the largest requirement consistent with any ordinal configuration.

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BibTeX
@misc{phaibulpanich2026wrong,
  title = {{How Wrong Can a Rank-Based Sample-Size Calculation Be? A Sharp Bound of 16/9 for Ordinal Outcomes}},
  author = {Akarin Phaibulpanich},
  howpublished = {arXiv},
  year = {2026},
  month = sep,
  doi = {10.48550/arxiv.2609.06575},
  eprint = {2609.06575},
  archivePrefix = {arXiv},
  url = {https://arxiv.org/abs/2609.06575},
}
RIS
TY  - UNPB
TI  - How Wrong Can a Rank-Based Sample-Size Calculation Be? A Sharp Bound of 16/9 for Ordinal Outcomes
AU  - Akarin Phaibulpanich
PY  - 2026
DA  - 2026/09/06
PB  - arXiv
DO  - 10.48550/arxiv.2609.06575
UR  - https://arxiv.org/abs/2609.06575
AB  - Rank-based tests need no distributional assumptions to be valid, but the sample size they require does depend on the shapes of the two outcome distributions, which are unknown at the design stage. Standard practice substitutes a variance calibrated under the null. We ask how wrong that substitution can be. Writing Π for the ratio of the true asymptotic variance of the estimated relative effect to the substituted one, we prove that under balanced allocation Π≤ 16θ(1−θ)/{2+θ(1−θ)} ≤ 16/9 for all ordinal distributions in any number of categories: within the first-order asymptotic calculation the required sample size can exceed the calculated one by at most 77.8%, and an explicit two-point family attains the bound at every effect size. The effect-specific envelope, not the constant, is the operative quantity for a design: the ceiling falls to $1.63$ at θ=0.65 and $1.37$ at θ=0.75, so a trial powered for a larger effect is correspondingly less exposed. The proof is elementary. In five extracted trial comparisons and 4,711 generated alternatives the realized cost stays within a few percent, because the extremal configuration is one that shift-type treatment mechanisms do not produce. These facts are complementary, and fix how the bound should be used: it is a design sensitivity certificate, not an inflation factor. A protocol can report the conventional sample size alongside the largest requirement consistent with any ordinal configuration.
ER  -