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Peer-reviewedCC BY 4.0Frontiers in Surgery

A treatment protocol for giant ventral hernias based on predicted postoperative respiratory function

4 affiliations
  1. 1Department of General and Digestive Surgery, Hospital de Antequera, Málaga, Spain
  2. 2DOXA Microfluidics, Málaga, Spain
  3. 3Department of Anesthesiology, Hospital de Antequera, Málaga, Spain
  4. 4Department of Radiology, Hospital de Antequera, Málaga, Spain

Abstract

Background: Giant ventral hernias and loss-of-domain abdominal wall defects remain challenging because reintegration of hernia contents may increase intra-abdominal pressure and impair postoperative respiratory function.

Methods/protocol: We describe a structured institutional protocol that integrates abdominopelvic CT volumetry, the hernia sac/abdominal cavity volume ratio, respiratory function testing during progressive simulated abdominal occupation, preoperative botulinum toxin, progressive pneumoperitoneum, transversus abdominis release and, only in selected high-risk cases, volume transposition.

Clinical implications: The protocol is intended to support individualized surgical planning by estimating both abdominal and respiratory consequences before definitive reconstruction.

Conclusions: This manuscript should be interpreted as a methodological protocol and feasibility proposal rather than a validated predictive clinical model. Prospective validation with standardized endpoints is ongoing and will be required before the thresholds can be considered externally validated.

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BibTeX
@article{lara2026treatment,
  title = {{A treatment protocol for giant ventral hernias based on predicted postoperative respiratory function}},
  author = {F. J. Pérez Lara and F. J. Moya Donoso and R. Zubizarreta Jiménez and E. Ojeda Leiva and F. J. Muñoz Castillo and C. Rueda Cruces and C. Ríos Navas},
  journal = {Frontiers in Surgery},
  year = {2026},
  month = oct,
  doi = {10.3389/fsurg.2026.1814887},
  url = {https://doi.org/10.3389/fsurg.2026.1814887},
  note = {CC BY 4.0},
}
RIS
TY  - JOUR
TI  - A treatment protocol for giant ventral hernias based on predicted postoperative respiratory function
AU  - F. J. Pérez Lara
AU  - F. J. Moya Donoso
AU  - R. Zubizarreta Jiménez
AU  - E. Ojeda Leiva
AU  - F. J. Muñoz Castillo
AU  - C. Rueda Cruces
AU  - C. Ríos Navas
PY  - 2026
DA  - 2026/10/12
JO  - Frontiers in Surgery
DO  - 10.3389/fsurg.2026.1814887
UR  - https://doi.org/10.3389/fsurg.2026.1814887
AB  - Background: Giant ventral hernias and loss-of-domain abdominal wall defects remain challenging because reintegration of hernia contents may increase intra-abdominal pressure and impair postoperative respiratory function.  Methods/protocol: We describe a structured institutional protocol that integrates abdominopelvic CT volumetry, the hernia sac/abdominal cavity volume ratio, respiratory function testing during progressive simulated abdominal occupation, preoperative botulinum toxin, progressive pneumoperitoneum, transversus abdominis release and, only in selected high-risk cases, volume transposition.  Clinical implications: The protocol is intended to support individualized surgical planning by estimating both abdominal and respiratory consequences before definitive reconstruction.  Conclusions: This manuscript should be interpreted as a methodological protocol and feasibility proposal rather than a validated predictive clinical model. Prospective validation with standardized endpoints is ongoing and will be required before the thresholds can be considered externally validated.
SN  - 2296-875X
ER  -