PreprintCC BY 4.0arXiv
On the Increased and Decreased Connectivity of the Demented Human Brain
Abstract
With major advances in cerebral imaging techniques, a large amount of data is available for studying the aging and demented brain. In this contribution, we apply the OASIS-3 dataset to identify small areas of human gray matter with higher or lower structural connectivity in dementia. As was anticipated, we have found that finer structures of the hippocampus and the temporal lobe have decreased connectivity in dementia. More surprisingly, the precuneus, the cuneus, and some finer structures of the insula, the paracentral lobule, and the precentral and paracentral gyri showed higher connectivity in dementia than in healthy subjects.
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BibTeX
@misc{hegedus2026increased,
title = {{On the Increased and Decreased Connectivity of the Demented Human Brain}},
author = {Daniel Hegedus and Marton Barnabas Mora and Balint Varga and Vince Grolmusz},
howpublished = {arXiv},
year = {2026},
month = sep,
doi = {10.48550/arxiv.2607.05654},
eprint = {2607.05654},
archivePrefix = {arXiv},
url = {https://arxiv.org/abs/2607.05654},
note = {CC BY 4.0},
}
RIS
TY - UNPB
TI - On the Increased and Decreased Connectivity of the Demented Human Brain
AU - Daniel Hegedus
AU - Marton Barnabas Mora
AU - Balint Varga
AU - Vince Grolmusz
PY - 2026
DA - 2026/09/09
PB - arXiv
DO - 10.48550/arxiv.2607.05654
UR - https://arxiv.org/abs/2607.05654
AB - With major advances in cerebral imaging techniques, a large amount of data is available for studying the aging and demented brain. In this contribution, we apply the OASIS-3 dataset to identify small areas of human gray matter with higher or lower structural connectivity in dementia. As was anticipated, we have found that finer structures of the hippocampus and the temporal lobe have decreased connectivity in dementia. More surprisingly, the precuneus, the cuneus, and some finer structures of the insula, the paracentral lobule, and the precentral and paracentral gyri showed higher connectivity in dementia than in healthy subjects.
ER -