Family based screening and smoking cessation for COPD detection: Hybrid cross-sectional and single-arm, multicenter intervention study.

@article{rabadecastedo2026family,
  title = {{Family based screening and smoking cessation for COPD detection: Hybrid cross-sectional and single-arm, multicenter intervention study.}},
  author = {Carlos Rábade-Castedo and Carlota Rodríguez-García and Paula Lado-Argibay and Goretti Fernández-Morón and Patricia Susana Vázquez-Millán and Juana Antonia Fernández-Moreno and Tara Pereiro-Brea and Sandra Buján-Garmendia and María Cruz Carbajales-Bouzón and María José Breijo-Pena and Elivia Canosa-Santos and Tamara Varela-Sanda and Elena Fernández-Fernández and Laura Vela-Flórez and José Rubén Blanco-Rodríguez and Marta Dablanca-Pallares and Pablo Mascareñas-Pazos and María Elena Toubes-Navarro and Carlos Zamarrón-Sanz and Luis Valdés-Cuadrado},
  journal = {Tobacco induced diseases},
  year = {2026},
  month = oct,
  doi = {10.18332/tid/235829},
  url = {https://europepmc.org/article/MED/42953757},
  note = {CC BY},
}

TY  - JOUR
TI  - Family based screening and smoking cessation for COPD detection: Hybrid cross-sectional and single-arm, multicenter intervention study.
AU  - Carlos Rábade-Castedo
AU  - Carlota Rodríguez-García
AU  - Paula Lado-Argibay
AU  - Goretti Fernández-Morón
AU  - Patricia Susana Vázquez-Millán
AU  - Juana Antonia Fernández-Moreno
AU  - Tara Pereiro-Brea
AU  - Sandra Buján-Garmendia
AU  - María Cruz Carbajales-Bouzón
AU  - María José Breijo-Pena
AU  - Elivia Canosa-Santos
AU  - Tamara Varela-Sanda
AU  - Elena Fernández-Fernández
AU  - Laura Vela-Flórez
AU  - José Rubén Blanco-Rodríguez
AU  - Marta Dablanca-Pallares
AU  - Pablo Mascareñas-Pazos
AU  - María Elena Toubes-Navarro
AU  - Carlos Zamarrón-Sanz
AU  - Luis Valdés-Cuadrado
PY  - 2026
DA  - 2026/10/22
JO  - Tobacco induced diseases
DO  - 10.18332/tid/235829
UR  - https://europepmc.org/article/MED/42953757
AB  - Chronic obstructive pulmonary disease (COPD) is the third leading cause of morbidity and mortality, making early detection crucial to improving prognosis. This study aimed to identify new cases of COPD, clinical profiles, and predictors among smokers and their cohabiting family members seeking help to quit smoking. A hybrid cross-sectional and single-arm intervention study was conducted over one year across 8 Primary care centers in the Santiago-Barbanza health area (Galicia, Spain), including 217 participants (index smokers and cohabitants without contraindications for spirometry). Clinical variables for diagnosis and characterization of the patient with COPD were analyzed, as well as variables associated with smoking (degree of smoking, motivation, nicotine dependence or abstinence at 6 months). The intervention involved: 1) performing forced spirometry on active smokers and cohabitants exposed to tobacco smoke for >20 years; and 2) enrolling smoking family members into a cessation program. Descriptive statistics, univariate analysis, and multivariate logistic regression were used to identify independent risk factors (adjusted odds ratio, AOR, and 95% CI). Out of 217 participants (104 family members), 147 (67.8%) were active smokers. Over 40% reported respiratory symptoms, with dyspnea being the most frequent. Spirometric abnormalities were present in 99 participants (45.6%), identifying 53 new COPD cases (24.4%), with 58.5% in the mild stage (GOLD I). Among cohabitants, 17 additional cases (15%) were detected regardless of smoking status. Cumulative smoking exposure time (AOR=1.04; 95% CI: 1.03-1.10; p=0.006) and respiratory symptoms (AOR=3.90; 95% CI: 1.25-10.00; p=0.036) were independent risk factors. This strategy led to the inclusion of 38 additional smokers in the cessation program, 25 of whom successfully quit. Active screening for COPD in smokers and their cohabitants facilitates early-stage diagnosis, potentially altering disease progression while increasing family engagement in smoking cessation programs.
SN  - 2070-7266
SN  - 1617-9625
ER  -