Peer-reviewedLicence not statedNature structural & molecular biology
De novo design of semisynthetic conduction pores
7 affiliations
- 1Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, USA
- 2Cardiovascular Research Institute, University of California, San Francisco, San Francisco, USA
- 3Oxford Nanopore Technologies plc, Oxford, UK
- 4Institute for Neurodegenerative Diseases, University of California San Francisco, San Francisco, USA.
- 5Department of Neurology, University of California San Francisco, San Francisco, USA.
- 6Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, USA.
- 7Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, USA.
Related
- De novo Rubisco design with protein language models
- 1017 Computational design of de novo antigen-specific T cell receptors using AI optimization and long-time-scale molecular simulations for targeted cancer immunotherapy
- Aptamers without SELEX: De novo design from protein structure in hours
- De novo design of miniprotein inhibitors of bacterial adhesins
- De novo design of allosterically controlled enzymes
BibTeX
@article{schnaider2026novo,
title = {{De novo design of semisynthetic conduction pores}},
author = {Lee Schnaider and A. Katherine Hatstat and Alistair J. Scott and Sophia K. Tan and Richard G. Hambley and William M. Dawson and Rhys C. Griffiths and Rian C. Kormos and Arthur A. Melo and Eric Tse and Nicholas F. Polizzi and E. Jayne Wallace and Gregory E. Merz and William F. DeGrado},
journal = {Nature structural \& molecular biology},
year = {2026},
month = sep,
doi = {10.1038/s41594-026-01881-w},
url = {https://doi.org/10.1038/s41594-026-01881-w},
}
RIS
TY - JOUR
TI - De novo design of semisynthetic conduction pores
AU - Lee Schnaider
AU - A. Katherine Hatstat
AU - Alistair J. Scott
AU - Sophia K. Tan
AU - Richard G. Hambley
AU - William M. Dawson
AU - Rhys C. Griffiths
AU - Rian C. Kormos
AU - Arthur A. Melo
AU - Eric Tse
AU - Nicholas F. Polizzi
AU - E. Jayne Wallace
AU - Gregory E. Merz
AU - William F. DeGrado
PY - 2026
DA - 2026/09/21
JO - Nature structural & molecular biology
DO - 10.1038/s41594-026-01881-w
UR - https://doi.org/10.1038/s41594-026-01881-w
SN - 1545-9993
SN - 1545-9985
ER -