Biochemistry & molecular biology
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- Mouse macrophages lacking both Pak1 and Pak2 exhibit preserved chemotaxis despite a strikingly altered migration mode
- Structural basis for dAMP specificity of the anti-phage deaminase KomA
- Pyk2 scaffolding relieves Src autoinhibition to coordinate reciprocal kinase activation
- Exogenous antimicrobial straight-chain unsaturated fatty acids promote low-temperature growth of Staphylococcus aureus
- Bifunctional cytochrome P450/ferredoxin is required for fungal phytochrome assembly at mitochondria
- BMP2 and BMP6 prodomains are essential to generate heterodimers in liver endothelial cells and associate with ligands after cleavage and secretion
- Ubiquitin ligase CHFR impairs Tie2 signaling via K48-linked ubiquitylation and degradation of Akt1 in endothelial cells
- Transfer of carotenoids to mitochondria by GRAMD1B improves resilience to photo-oxidative stress in 661W cone photoreceptor cells
- IL-6 Trans-Signaling Promotes Posterior Capsule Repopulation by Lens Epithelial Cells Through JAK-STAT3 Signaling
- Targeting CLDN3 Enhances PD-1 Blockade Efficacy in Gastric Cancer by Disrupting the NF-κB/p65–CXCL1–PD-L1 Immune Evasion Axis
- Becoming Messengers: cAMP, Ca2+, and the Emergence of Cellular Control
- Hypoxia alters the synthesis and post-translational modification of collagens in human coronary artery smooth muscle cells
- Distinct proteomic and acylproteomic adaptations to succinate dehydrogenase loss in two cell contexts
- A Novel Drp1-Golph2 Tether Mediates Mitochondria-Golgi Spatial Association to Orchestrate Mitochondrial Function and Hepatic Lipid Catabolism Across Vertebrates
- Differential chromatin enrichment of histone H3K27me3 underlies variable cell responses to estrogen and endocrine treatment
- Embryonic stem cells do not have a globally disrupted higher-order chromatin fiber structure
- From epidemiology to mechanisms of inflammation in hypertensive cardiac damage
- A Phenomenological Model of Synaptic Activity in the Blowfly Lamina
- Upstream ORFs as Regulators of Viral Replication
- Kynureninase Is a Prognostic Biomarker of Poor Survival and Gemcitabine Resistance in Pancreatic Ductal Adenocarcinoma
- Comparative Analysis of Conformational Dynamics and Nucleotide Binding in miniGαi1 and Full-Length Gαi1
- Engineering Lipid Nanoparticles Beyond ApoE-Mediated Liver Tropism: Design Strategies for Extrahepatic and Organ-Selective Delivery
- Age-Related and Region-Specific Morphological and Molecular Alterations of Astrocytes and Microglia Following Chronic Oxidative Stress in Male Wistar Rats
- Natural Bitter Compounds, Intestinal TAS2Rs, and GLP-1 Secretion: Mechanistic Evidence and Translational Challenges
- Biphasic Modulation of Absence Seizures by Lisuride in GAERS: Dissecting the Role of 5-HT2A Receptors