Biochemistry & molecular biology
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- PADI2 facilitates progression and cisplatin resistance of epithelial ovarian cancer via m6A methylation
- High-Throughput Plasma Proteomic Profiling Identifies Novel Biomarker Candidates in Parkinson’s Disease with Cognitive Decline
- White-tailed deer milk promotes rapid SARS-CoV-2 RNA degradation through synergistic ionic and enzymatic mechanisms
- Cardioprotective effects of 3-N-Butylphthalide in diabetic cardiomyopathy: focus on balanced mitochondrial dynamics and pyroptosis pathways
- Modulation of G6PD-mediated Vitamin C Sensitivity in Small Cell Lung Cancer by the AKT/NRF2 axis
- European robin cryptochrome 4a does not bind 8-HDF or MTHF as second antenna chromophores
- T cell transcriptomes in simulated microgravity in vivo
- Site-comprehensive phosphorylation dismantles a disordered interaction hub to drive Cdc25C activation
- The RNA and protein landscapes of mouse brain organoids
- Characterization of lysine methylation during neuronal differentiation of LUHMES cells
- Targeted degradation of a constitutively active GPCR oncoprotein
- Human MutLα activates methylpurine DNA glycosylase to induce alkylation damage cytotoxicity
- Guardians of splicing: quality control mechanisms of snRNA variants
- MCM10 and RECQL4 have cooperative and redundant roles in activating the CMG helicase during the replication initiation
- Mouse macrophages lacking both Pak1 and Pak2 exhibit preserved chemotaxis despite a strikingly altered migration mode
- Structural basis for dAMP specificity of the anti-phage deaminase KomA
- Pyk2 scaffolding relieves Src autoinhibition to coordinate reciprocal kinase activation
- Exogenous antimicrobial straight-chain unsaturated fatty acids promote low-temperature growth of Staphylococcus aureus
- Bifunctional cytochrome P450/ferredoxin is required for fungal phytochrome assembly at mitochondria
- BMP2 and BMP6 prodomains are essential to generate heterodimers in liver endothelial cells and associate with ligands after cleavage and secretion
- Ubiquitin ligase CHFR impairs Tie2 signaling via K48-linked ubiquitylation and degradation of Akt1 in endothelial cells
- Transfer of carotenoids to mitochondria by GRAMD1B improves resilience to photo-oxidative stress in 661W cone photoreceptor cells
- IL-6 Trans-Signaling Promotes Posterior Capsule Repopulation by Lens Epithelial Cells Through JAK-STAT3 Signaling
- Targeting CLDN3 Enhances PD-1 Blockade Efficacy in Gastric Cancer by Disrupting the NF-κB/p65–CXCL1–PD-L1 Immune Evasion Axis
- Becoming Messengers: cAMP, Ca2+, and the Emergence of Cellular Control