Biochemistry & molecular biology
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- Conserved IQ motifs, divergent apo-calmodulin recognition in UBE3B and UBE3C.
- The Senokine Gas6 Promotes Aortic Valve Calcification Through CaMKII-DRP1-Mediated Terminal Scission of Mitochondrial-Derived Vesicles.
- Automated reconstruction of reproducible protein databases with RepDBmaker.
- Impact of YAQ001 on the Gut Microbiome, Permeability and Markers of Systemic Inflammation in Patients With Cirrhosis.
- A Müller Glia-Retinal Pigment Epithelium Apical Network Surrounding Cone Outer Segments in Fish and Mouse.
- Stress hyperglycemia impairs FOXK2-dependent macrophage cardiac repair after myocardial infarction
- One factor, two safeguards: RUNX1 divides its labor across the regulatory genome
- Single-cell multi-omics reveals archetypal regulatory programs shared across T cell subsets
- RAStoERK: A reference interaction atlas for insights into signaling and disease
- Baseline microbial ecology encodes probiotic responsiveness through distinct metabolic and network configurations
- UFSP2 constitutes a targetable vulnerability via deUFMylation-dependent activation of AKT oncogenic signaling
- Cryo-EM and biochemical characterization of a BRAF/CRAF heterodimer shows that the NtA motif negative charge is dispensable for RAF activation
- Single-nucleus RNA sequencing in ischemic cardiomyopathy reveals common transcriptional profile underlying end-stage heart failure
- ALKBH8 promotes acute myeloid leukemia progression by coupling codon-dependent translation elongation to mRNA stability
- RIF1 coordinates the stepwise post-replicative H3K9me3 recovery
- Programmed DNA breaks drive chromatin reconfiguration and facilitate transcriptional potentiation at neuronal early response genes
- Interaction of Discoidin Domain Receptor 1 with a 14-3-3-Beclin-1-Akt1 Complex Modulates Glioblastoma Therapy Sensitivity
- SMURFs regulate mesendoderm differentiation through SMAD2-dependent ubiquitination of CDK9
- The conserved NUS-1/DHDDS-1 complex links N-glycosylation to lipid and lysosomal homeostasis in C. elegans
- Sequential TPRX1 and HERVL activation delineates a progression toward the totipotent-like state
- Circular RNAs in Drug-Induced Cardiotoxicity: Roles, Mechanisms, and Therapeutic Potential.
- Diabetic Polyneuropathy Patients Exhibit an Altered Skeletal Muscle Proteome Phenotype.
- No lysine? No problem: the surprising roles of WNK kinases in physiology and disease.
- CellPatch: a flexible and efficient framework for single-cell foundation models empowered by heuristic gene patching
- Revealing a sustained increase in relative avian forelimb length through the Mesozoic