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Bioinformatics & computational biology

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2,083 studies

  1. Rapid, accurate, and memory-frugal sub-gene-level quantification of probe-based, multiplexed single-cell data
    D. He, Y. Gao, R. Patro
    bioRxivPreprintCC BY-NC-NDFull textBioinformatics & computational biologybioRxiv
  2. Agentic AI enables cell segmentation-free cell-type inference and cell-type-guided cell segmentation in spatial transcriptomics
    Y. Jeong, H. Lee, D. Lee +10
    bioRxivPreprintCC BY-NDFull textBioinformatics & computational biologybioRxiv
  3. Residual barcode-like sequences and barcode-associated artifacts after Dorado and Barbell preprocessing of metagenomic reads
    T. Dinse, V. R. Englaender, S. Metz +2
    bioRxivPreprintCC BYFull textBioinformatics & computational biologybioRxiv
  4. Predicting Transcriptional Responses to Unseen Compounds through Context Modeling and Multi-View Transfer
    Y. Lei, H. Liang, K. Peng +1
    bioRxivPreprintCC BY-NCFull textBioinformatics & computational biologybioRxiv
  5. Growing a Root from Its Genome : Emergent Tissue Layers and Zones in a GPU-Native Simulation of the Arabidopsis Root Tip
    E. Auger, M. Gandecki, F.-X. Heng
    bioRxivPreprintCC BY-NC-NDFull textBioinformatics & computational biologybioRxiv
  6. Hybrid RY-mers increase aDNA alignment sensitivity
    I. Tolstoganov, K. Sahlin
    bioRxivPreprintCC BYFull textBioinformatics & computational biologybioRxiv
  7. Towards a foundation model for raw nanopore signal through discrete tokenization
    G. Cheng, E. Pitkänen
    bioRxivPreprintCC BYFull textBioinformatics & computational biologybioRxiv
  8. QRAFT: Scaling coalescent-based species tree inference to one million taxa
    A. Rahman, A. Saha, M. S. Bayzid
    bioRxivPreprintCC BY-NC-NDFull textBioinformatics & computational biologybioRxiv
  9. Theoretical prediction of assembly contiguity
    M. H. Abrar, P. Medvedev, A. Novikov +1
    bioRxivPreprintCC BYFull textBioinformatics & computational biologybioRxiv
  10. QUANTA: A quantum annealing framework for species tree estimation using weighted quartet amalgamation
    N. Kumar Mondal, M. S. Bayzid
    bioRxivPreprintCC BYFull textBioinformatics & computational biologybioRxiv
  11. scCont: Interpretable Contrastive Learning for Functional Characterization of Cellular State Transitions
    N. Kewalramani, S. Wuchty, M. Crovella +2
    bioRxivPreprintCC BY-NCFull textBioinformatics & computational biologybioRxiv
  12. Leveraging deep generative modelling at the agent level in discrete-event simulations
    Margherita Molaro, Matthew M. Graham, Oliver Watson +6
    arXivPreprintCC BY 4.0Full textBioinformatics & computational biologyEvolutionary biologyarXiv
  13. PharmAgents2: Towards Autonomous End-to-End Drug Discovery
    Haichuan Tan, Bowen Gao, Tao Huang +22
    arXivPreprintCC BY-NC-ND 4.0Full textBioinformatics & computational biologyarXiv
  14. How Deep is the Signal? Time-Context up to 30 Years for Colorectal Cancer Prediction in a Primary-Care EHR Model
    Achille Raviez, Lan Wang, Brendan Delaney
    arXivPreprintCC BY 4.0Full textBioinformatics & computational biologyarXiv
  15. scDNM-VAE enables directly inspectable deep clustering of single-cell RNA-seq data through signed dendritic gating
    Melih Agraz, Deniz Karapinar, Aysel Topsir +3
    arXivPreprintCC BY-NC-ND 4.0Full textBioinformatics & computational biologyGenetics & genomicsarXiv
  16. Interpretable many-body interaction laws for collective motion from few trajectories
    Timon S. Gutleb
    arXivPreprintarXiv licenceFull textBioinformatics & computational biologyarXiv
  17. Pattern selection and biomass shifts in a vegetation model with nonlocal competition and Allee activation
    Federico Dimatz, Marcelo N Kuperman
    arXivPreprintarXiv licenceFull textBioinformatics & computational biologyarXiv
  18. Unveiling Molecular Basis of Terminalia chebula in Modulating the AGE-RAGE-PRKCB Axis in Diabetic Nephropathy: Integrative Network Pharmacology and Computational Study
    S. M. Riaduzzaman Niaz, Sumaia Jannat, Sheikh Abdullah Al Ashik +1
    PLOS OnePeer-reviewedCC BY 4.0Bioinformatics & computational biologyCell biologyPLOS
  19. A pretreatment ECM-high/immune-low transcriptomic score is associated with pathological complete response after neoadjuvant therapy in breast cancer
    Tao Wang, Xiaoyun Wu
    PLOS OnePeer-reviewedCC BY 4.0Bioinformatics & computational biologyCell biologyPLOS
  20. Early terminated transcripts and missing proteins reflect artifacts in bacterial proteomes
    Giuseppe Insana, Maria J Martin, William R Pearson
    NAR Genomics and BioinformaticsPeer-reviewedCC BY-NC 4.0Full textBioinformatics & computational biologyCrossrefPMC
  21. Learning Constraints in Protein Evolution beyond Known Substitution Frequencies
    Raphaël Bricout, Hugues Roest Crollius, Auguste Genovesio
    Molecular Biology and EvolutionPeer-reviewedCC BYFull textBioinformatics & computational biologyEcologyEvolutionary biologyHAL
  22. RadMultiBench: A Reproducible Dual-Task Benchmark Exposing the Limits of Pre-Trained Vision-Language Models Across Thoracic and Breast Imaging
    M. N. Alam, M. T. Rahman, D. Sarkar +3
    bioRxivPreprintCC BYFull textBioinformatics & computational biologybioRxiv
  23. Organotchi: an open-source tool for the automated segmentation, morphological characterization, and longitudinal tracking of organoids
    L. Branco, T. Lautenschlager, D. Andreeva +9
    bioRxivPreprintCC BYFull textBioinformatics & computational biologybioRxiv
  24. TailEnrich enables discovery of dysregulated genes through disease sample enrichment testing
    H. Li, Y. Liu, C. Lin +3
    bioRxivPreprintCC BY-NC-NDFull textBioinformatics & computational biologybioRxiv
  25. DisCell: Separating Spillover from Niche Response in Spatial Transcriptomics
    R. Molen, H. Toosi, P. F. Ferreira +1
    bioRxivPreprintCC BYFull textBioinformatics & computational biologybioRxiv