Oncology
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- Neuroblastoma-derived Extracellular Vesicles Disrupt the Integrity of Central Nervous System Barriers via Tight Junction Modulation
- FANCM restrains structural genome evolution and defines a synthetic lethal dependency in BRCA1-deficient breast cancer
- Preclinical trial supports dual inhibition of BCL2 and Aurora kinase A for MYCN-amplified high-risk neuroblastoma
- An RGS5-positive fibroblast to WNT-like epithelial TGFB axis in colorectal liver metastasis, replicated in an independent paired cohort
- Quantitative and sensitive neuroblastoma minimal residual disease detection using extrachromosomal DNA (ecDNA) breakpoints
- Deep Learning-based Modeling Enhances Efficacy of Natural Ligand CAR Binders Targeting CD70
- Melittin-induced membrane disruption in hepatocellular carcinoma involves mtROS/GSDME-mediated pyroptosis
- SUMOylation is a Therapeutic Vulnerability in High-risk Neuroblastoma
- Stochastic Boolean Model of Death Signaling in MCF7:5C Predicts Cell Death Inducers and Inhibitors
- Loss of short-form Ron promotes B and T cell cooperation to prevent outgrowth of breast cancer bone metastasis
- The small molecule inhibitor SU056-mediated targeting of YB1 inhibits the Rb pathway in triple-negative breast cancer tumors
- Targeting FEN1 disrupts EIF4A3-mediated MUC1-C autoregulation: a novel strategy to suppress lung adenocarcinoma progression.
- Involvement of Protein Kinase C Delta and Monocarboxylate Transporter 4 in the Development of Statin-Induced Cytotoxicity in a Rhabdomyosarcoma-Derived Cell Line
- Exploring patient perspectives of exercise in advanced pancreatic cancer care in Canada: A qualitative interpretive description
- Activation of PP2A-B56α leads to aberrant EGFR signaling and proliferative phenotypes in PDAC
- An Oxidative Stress-Associated Seven-Gene Prognostic Signature in Lung Adenocarcinoma: Integrative Transcriptomic Analysis Across Public Cohorts
- Interplay of NuA4/TIP60 and PRC2 Complex Activities in Fusion Driven Endometrial Stromal Sarcoma
- G-quadruplex targeting by CX-5461 as a novel therapeutic strategy in testicular germ cell tumors
- HUMAN-LIKE SIALOME REMODELING LINKS HYPERGLYCEMIA TO COLORECTAL CANCER PROGRESSION
- Tumor-derived SAA1-TLR4 signaling drives tumor-to-muscle communication in pancreatic cancer cachexia
- Stepwise bladder carcinogenesis reveals transcriptional reprogramming involving MMP1 and COL7A1
- Spatial multi-omics resolve epithelium-fibroblast gradients and highlight NESTIN-NOTCH1-expressing subepithelial fibroblasts during human pancreatic tumorigenesis
- Genetic and structural interpretation of NLRP1 FIIND domain variants in glioma in an Indian cohort: a pilot study
- Co-translational O-glycosylation driven by GALNTs spatial reprogramming fosters pancreatic cancer growth
- Targeting fibroblast activation suppresses chemotherapy-induced pro-invasive remodeling of the extracellular matrix