Pharmacology & toxicology
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- Strategic selection of TPD technologies based on disease pathology: from mechanistic diversity to clinical implementation
- Multidimensional analysis of the pathological mechanisms of infantile hemangioma: metabolic reprogramming, immune remodeling, and programmed cell death
- Traditional Paeonia radix alba formulas and their bioactive metabolites: a narrative review focusing on hepatoprotection in chronic liver diseases
- Editorial: 4Rs in ethnopharmacology - reduce, refine, replace and responsibility using animal models
- Progression-free survival of 23 months with second-line trastuzumab deruxtecan in HER2-positive gastroesophageal junction adenocarcinoma: a case report
- Justicia procumbens suppresses high-fat diet-induced weight gain in mice and adipogenesis in 3T3-L1 cells with inhibition of AKT and STAT3 phosphorylation
- A tumor-responsive nanoplatform orchestrating multiplexed macrophage engagers and immune checkpoint blockade for triple-negative breast cancer immunotherapy
- Tanshinone IIA in colorectal cancer: preclinical mechanisms, therapeutic sensitization, and translational prospects
- Sulodexide versus low-molecular-weight heparin in critically ill neonates: a propensity score–matched retrospective cohort study
- Effect of compound kushen injection on immune function in patients with lung cancer: a systematic review and meta-analysis
- Oral anticoagulants and the risk of acute kidney injury: a retrospective real-world cohort study using overlap propensity score weighting
- Paeoniflorin ameliorates Parkinson’s disease by promoting autophagy to inhibit A1 phenotype astrocyte activation
- Engineering a multifunctional LL37-TP5 hybrid peptide with potent antimicrobial endotoxin-neutralizing and anti-inflammatory properties
- Human amniotic mesenchymal stem cell-derived exosomes alleviate cerebral Palsy–Associated neuronal damage via TSC1/mTOR/ULK1 autophagy suppression and PINK1/Parkin mitophagy restoration
- Review of oregano essential oils: pharmacological activities and applications
- From recognition to delivery: nucleic acid aptamers in miRNA-related diagnosis and therapy of hepatocellular carcinoma
- Magnesium cantharidate suppresses hepatocellular carcinoma progression and modulates tumor-associated macrophage polarization: potential involvement of ERK1/2 signaling and de novo serine synthesis
- Development and qualification of recombinant Göttingen Minipig CYP3A22 and CYP3A29
- Patterns of proton pump inhibitor prescription: a retrospective study from a tertiary hospital in Saudi Arabia
- Integrated transcriptomic and proteomic profiling of RXRA-overexpressing chronic myeloid leukemia cells identifies protein kinase D as a candidate target for imatinib sensitization
- Raddeanin A is associated with enhanced anti-tumor efficacy of doxorubicin in a murine breast cancer model by modulating MDR1 expression
- Crosstalk between Nrf2 and miRNAs in oxidative stress, cancer progression, and therapy resistance
- Single-cell RNA sequencing identifies stem-like subpopulations and their gene signature in lung adenocarcinoma progression
- Protective effects and underlying mechanisms of naringenin in myocardial ischemia/reperfusion injury: a systematic review and preclinical meta-analysis
- PD-1 and its ligands in ILC2-mediated airway inflammation in asthma: context-dependent mechanisms and therapeutic implications