Pharmacology & toxicology
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- Mechanisms involved in the sex-dependent dopaminergic neurodegeneration induced by MDMA in a mouse model of adolescent drug exposure
- From prediction to functional delivery: evaluating artificial intelligence in lipid nanoparticle design
- Incomplete linkage disequilibrium between DPYD HapB3 variants: implications for pharmacogenetic phenotype assignment
- Elsholtzia Bodinieri vaniot dichloromethane extract exerts anti-inflammatory effects in acute lung injury mice by regulating the CCR1 and FLT1
- Protective effects of AKBA against hypoxia-induced cognitive dysfunction: potential involvement of SLC2A1, PTGS1, and BCL2L1
- Targeting MicroRNAs in the perioperative window to prevent surgery-induced metastasis and postoperative cancer recurrence
- The next frontier of peptide therapeutics: from targeted conjugates (PDC/ODC) to AI-driven safety-by-design
- SENP3 loss in biliary tract cancer chemoresistance: substrate-specific control of fatty acid oxidation and mitophagy
- Diterpenoid tanshinones enhance CD8+ T-cell-mediated antitumor immunity in gastric cancer by suppressing ENO1 activity and glycolysis
- Malus domestica fruit-derived vesicles extract protect against upstream cellular hallmarks of vascular inflammation and epithelial barrier dysfunction
- Morusin induces GSDME-dependent pyroptosis in non-small cell lung cancer via the angiotensin II receptor type 2
- Application of DASC and AUSC metrics in evaluating antimicrobial stewardship interventions in critically ill patients
- MechTox: an audited benchmark for ordinal drug-induced liver injury prediction with uncertainty and mechanism-oriented interpretation
- Comparable TXNIP-inhibiting, anti-apoptotic and anti-diabetic effects of TIX100 and its individual enantiomers
- Effectiveness of a pharmacist-led protocol to manage cystitis in women, in France: the PharmaCyst’ open-label, multicenter, randomized, controlled, cluster study
- Binary SiO2-CaO bioactive glass nanoparticles synthesis and colloidal stability investigated via in-situ SAXS for freeze-cast scaffolds
- Single-cell multi-omics reveals cellular atlases and cell–cell interaction networks in metabolic dysfunction-associated steatotic liver disease (MASLD)
- Cost-effectiveness of datopotamab deruxtecan versus chemotherapy as a first-line treatment for patients with advanced triple-negative breast cancer
- Ceftazidime–avibactam monotherapy versus combination therapy for carbapenem-resistant Gram-negative bacterial infections: a secondary meta-analysis of predominantly critically ill cohorts
- Results of Operating the 2025 "Heat-related Illness Emergency Department Surveillance System".
- Air pollution is associated with a distinct pathogen spectrum in community-acquired pneumonia: a prospective multicentre cohort study
- Shikonin: From Biosynthesis and Pharmacological Mechanisms to Translational Safety and Drug Delivery
- High‐Resolution Housing Data for Primary Prevention: What Address‐Level Records Add to National Lead‐Based‐Paint Screening
- PCB-Exposed Gut Microbiota Recapitulate Neurobehavioral Deficits and Reprogram Hippocampal Transcriptomic Signatures
- Closing the loop: a needs-assessment informed model for embedding a non-allergist penicillin allergy de-labelling service in acute medicine, a quality improvement report