Pharmacology & toxicology
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- Efficacy and safety of antibody-drug conjugates in pretreated HER2-positive advanced breast cancer: a network meta-analysis of randomized controlled trials
- Bioactive compounds from Perilla frutescens modulate multiple cell death pathways and signaling networks in cancer therapy
- Selective behavioral and prefrontal transcriptomic correlates of acute clozapine exposure in socially isolated mice
- Microbiota-based PBPK model: new approach methodology for assessing the kinetics of drugs and chemicals
- LKB1 promotes lung adenocarcinoma cell senescence by suppressing the O-GlcNAc glycosylation-mediated activation of telomerase
- MolecureAI: an agentic AI platform for autonomous drug discovery
- Indication-specific adverse event profiles of semaglutide and liraglutide: a FAERS disproportionality analysis
- The role of sitagliptin in modifying metabolic, hormonal and clinical parameters in polycystic ovarian syndrome patients: a randomized controlled trial
- Circular RNAs in cancer: from biomarkers to vaccine-based immunotherapy
- Differential functions of ROCK1 and ROCK2 in liver fibrosis and advances in targeted therapeutic strategies
- Statistical process control within the Six Sigma DMAIC framework for monitoring medication dispensing errors in hospital pharmacies: a Saudi case study
- Safety signals and CMV-related events reported during letermovir therapy: a FAERS database study
- Intranasal hydrogels for Alzheimer’s disease: from nasal-interface engineering to brain targeting and translational readiness
- Sanguinarine ameliorates rheumatoid arthritis by activating the Hippo-YAP/TAZ pathway to induce apoptosis and suppress inflammation in fibroblast-like synoviocytes
- Traditional Chinese medicine (TCM)-based nanoformulations for cancer therapy: antitumor mechanisms, challenges, and future directions
- Predictive biomarkers for precision treatment in rheumatoid arthritis: are we there yet?
- Clinical outcomes following a traditional Chinese medicine foot bath preparation for lower-limb edema and sleep disturbance: a single-center retrospective study of 2,000 patients
- B7-H3-mediated immune regulation in cancer: biological functions and therapeutic opportunities
- Case Report: Dasatinib-associated chylothorax and occult Bartonella henselae infection in pediatric leukemia: a case report and systematic review
- Comparative efficacy of Traditional Chinese Medicine classical prescriptions for angina pectoris: a network meta-analysis
- Mechanistic insights into the potential role of botanical drugs and plant-derived metabolites in mitigating oxidative stress in varicocele
- Efficacy and safety of lecanemab monoclonal antibody in the treatment of mild to moderate Alzheimer’s disease: a systematic review and meta-analysis
- Integrated proteomic and metabolomic analysis reveals the mechanism of astragalus complanatus flavonoids against liver fibrosis in rats
- Hepatoprotective Formula 919 ameliorates hepatic steatosis and metabolic disturbance in NAFLD with involvement of AMPK signaling
- Efficacy, mechanisms, and influence factors of small molecule targeted therapy in treating rheumatoid arthritis: a multi-dimensional clinical, immunological, and ultrasonographic study