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Peer-reviewedCC BYFrontiers in Medicine

Case Report: Fetal giant congenital hemangioma with arteriovenous malformation: to be or not to be

  • Peng Yue1
  • Peng Yue2
  • Fan Ma1
  • Li Ma1
  • Li Ma2
  • JiaoJiao Wan1
  • Xiaoliang Liu1
  • Xiaoliang Liu2
  • Fan Hu1
  1. 1Key Laboratory of Birth Defects and Related Diseases of Women and Children of MOE, Department of Pediatrics, West China Second University Hospital, Sichuan University, Chengdu, China
  2. 2Department of Pediatrics, West China Second University Hospital-Tianfu·Sichuan Provincial Children’s Hospital, Meishan City, Sichuan Province, China
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Abstract

ObjectiveThis study reports a rare and life-threatening case of a giant congenital hemangioma with arteriovenous fistula in a neonate and describes its clinical management and outcomes.MethodA female neonate with a giant right forearm hemangioma with arteriovenous fistula, detected prenatally at 23 weeks, was managed by a multidisciplinary team. Postnatally, the infant developed severe pulmonary hypertension and active bleeding from the mass. Diagnosis was confirmed via computed tomography angiography and arteriography. Emergency intervention with combined embolization coil and sclerotherapy was performed, followed by oral propranolol therapy.ResultsFollowing the combined intervention and pharmacotherapy, the condition of the infant improved significantly. The severe pulmonary hypertension resolved, and the tumor size progressively reduced.ConclusionCongenital hemangioma combined with arteriovenous malformation can lead to severe, life-threatening complications. A prompt, multidisciplinary approach involving embolization, sclerotherapy, and pharmacotherapy can achieve favorable outcomes, underscoring the importance of early recognition and integrated perinatal management.

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Cite

BibTeXRIS
BibTeX
@article{yue2026case,
  title = {{Case Report: Fetal giant congenital hemangioma with arteriovenous malformation: to be or not to be}},
  author = {Peng Yue and Peng Yue and Fan Ma and Li Ma and Li Ma and JiaoJiao Wan and Xiaoliang Liu and Xiaoliang Liu and Fan Hu},
  journal = {Frontiers in Medicine},
  year = {2026},
  month = oct,
  doi = {10.3389/fmed.2026.1925509},
  url = {https://doi.org/10.3389/fmed.2026.1925509},
  note = {CC BY},
}
RIS
TY  - JOUR
TI  - Case Report: Fetal giant congenital hemangioma with arteriovenous malformation: to be or not to be
AU  - Peng Yue
AU  - Peng Yue
AU  - Fan Ma
AU  - Li Ma
AU  - Li Ma
AU  - JiaoJiao Wan
AU  - Xiaoliang Liu
AU  - Xiaoliang Liu
AU  - Fan Hu
PY  - 2026
DA  - 2026/10/23
JO  - Frontiers in Medicine
DO  - 10.3389/fmed.2026.1925509
UR  - https://doi.org/10.3389/fmed.2026.1925509
AB  - ObjectiveThis study reports a rare and life-threatening case of a giant congenital hemangioma with arteriovenous fistula in a neonate and describes its clinical management and outcomes.MethodA female neonate with a giant right forearm hemangioma with arteriovenous fistula, detected prenatally at 23 weeks, was managed by a multidisciplinary team. Postnatally, the infant developed severe pulmonary hypertension and active bleeding from the mass. Diagnosis was confirmed via computed tomography angiography and arteriography. Emergency intervention with combined embolization coil and sclerotherapy was performed, followed by oral propranolol therapy.ResultsFollowing the combined intervention and pharmacotherapy, the condition of the infant improved significantly. The severe pulmonary hypertension resolved, and the tumor size progressively reduced.ConclusionCongenital hemangioma combined with arteriovenous malformation can lead to severe, life-threatening complications. A prompt, multidisciplinary approach involving embolization, sclerotherapy, and pharmacotherapy can achieve favorable outcomes, underscoring the importance of early recognition and integrated perinatal management.
SN  - 2296-858X
ER  -