Clinical Relevance of Atriogenic Tethering in Atrial Functional Mitral Regurgitation
Abstract
findings to decision-making.In this context, the findings of Omori et al. derived from the large-scale observational REVEAL-AFMR registry, provide valuable insights.6 In this issue of the Journal, they report a prevalence of AT (24%) among patients with moderate or greater AFMR, and AT's association with enlarged LV endsystolic dimension (LVESD) and greater left atrial diameter.Moreover, their study suggests an adverse prognostic impact of AT on clinical outcomes, including increased rates of cardiovascular death, heart failure hospitalizations, and mitral valve interventions.This study adds important new data to the clinical discussion regarding AT's role in AFMR.Current ACC/AHA and ESC/EACTS guidelines provide recommendations for the management of patients with chronic MR.Both guidelines support mitral valve surgery in symptomatic severe MR patients or asymptomatic patients with evidence of LV dysfunction.In addition, the ESC/EACTS guidelines specifically recognize AF and pulmonary hypertension as additional triggers for surgical consideration.These conditions commonly coexist in
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BibTeX
@article{kusunose2026clinical,
title = {{Clinical Relevance of Atriogenic Tethering in Atrial Functional Mitral Regurgitation}},
author = {Kenya Kusunose},
journal = {Circulation Journal},
year = {2026},
month = aug,
doi = {10.1253/circj.cj-25-0651},
url = {https://www.jstage.jst.go.jp/article/circj/90/9/90_CJ-25-0651/_article},
note = {CC BY-NC-ND},
}
RIS
TY - JOUR
TI - Clinical Relevance of Atriogenic Tethering in Atrial Functional Mitral Regurgitation
AU - Kenya Kusunose
PY - 2026
DA - 2026/08/25
JO - Circulation Journal
DO - 10.1253/circj.cj-25-0651
UR - https://www.jstage.jst.go.jp/article/circj/90/9/90_CJ-25-0651/_article
AB - findings to decision-making.In this context, the findings of Omori et al. derived from the large-scale observational REVEAL-AFMR registry, provide valuable insights.6 In this issue of the Journal, they report a prevalence of AT (24%) among patients with moderate or greater AFMR, and AT's association with enlarged LV endsystolic dimension (LVESD) and greater left atrial diameter.Moreover, their study suggests an adverse prognostic impact of AT on clinical outcomes, including increased rates of cardiovascular death, heart failure hospitalizations, and mitral valve interventions.This study adds important new data to the clinical discussion regarding AT's role in AFMR.Current ACC/AHA and ESC/EACTS guidelines provide recommendations for the management of patients with chronic MR.Both guidelines support mitral valve surgery in symptomatic severe MR patients or asymptomatic patients with evidence of LV dysfunction.In addition, the ESC/EACTS guidelines specifically recognize AF and pulmonary hypertension as additional triggers for surgical consideration.These conditions commonly coexist in
SN - 1347-4820
SN - 1346-9843
ER -