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Peer-reviewedCC BYJournal of Vascular and Interventional Radiology

Society of Interventional Radiology Position Statement on Genicular Artery Embolization for Symptomatic Knee Osteoarthritis

  • Osman S. Ahmed1
  • Bedros Taslakian2
  • Yuji Okuno3
  • Peter Minko4
  • Jafar Golzarian5
  • Sandeep Bagla6
  • Marc R. Sapoval7
  • Mateus P. Correa8
  • Mark Little9
  • Luke R. Wilkins10
  • Joel A. Block11
  • Brendon S. Ross12
4 more authors
  • Sara Wallace12
  • Magdalena Anițescu13
  • Charles Ray14
  • Siddharth A. Padia15
15 affiliations
  1. 1Joint and Vascular Institute, Libertyville, Illinois; Department of Radiology, Division of Interventional Radiology, University of Utah, Salt Lake City, Utah. Electronic address: [email protected]
  2. 2Department of Interventional Radiology, University of Miami Miller School of Medicine, Miami, Florida
  3. 3Okuno Clinic, Tokyo, Japan
  4. 4Department of Diagnostic and Interventional Radiology, University Duesseldorf, Medical Faculty, Duesseldorf, Germany
  5. 5North Star Vascular & Interventional, Minneapolis, Minnesota; University of Minnesota Medical School, Minneapolis, Minnesota
  6. 6Prostate Centers USA, Falls Church, Virginia
  7. 7Université Paris Cité, Paris, France
  8. 8Invasc - Instituto Vascular, Passo Fundo, Brazil
  9. 9Royal Berkshire NHS Foundation Trust, Reading, United Kingdom
  10. 10Department of Radiology, Division of Interventional Radiology, University of Virginia, Charlottesville, Virginia
  11. 11Section of Rheumatology, Department of Internal Medicine, Rush University Medical Center, Chicago, Illinois
  12. 12Department of Orthopaedic Surgery and Rehabilitation Medicine, University of Chicago, Chicago, Illinois
  13. 13Department of Anesthesia & Critical Care, Section of Pain Medicine, University of Chicago Medicine, Chicago, Illinois
  14. 14Department of Radiology and Imaging Sciences, Spencer Fox Eccles School of Medicine at University of Utah Health, Salt Lake City, Utah
  15. 15Division of Interventional Radiology, Department of Radiology, David Geffen School of Medicine at the University of California Los Angeles, Los Angeles, California
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Abstract

Knee osteoarthritis (KOA) is a prevalent musculoskeletal condition characterized by a significant therapeutic gap between the failure of conservative medical therapies and surgical arthroplasty. Contemporary evidence supports a model in which chronic synovitis and pathologic neoangiogenesis, closely coupled to perivascular nociceptive nerve growth, serve as significant contributors of pain and peripheral sensitization in KOA. Genicular artery embolization has emerged as a targeted, joint-preserving vascular intervention performed by interventional radiologists that directly addresses the inflammatory and neurovascular components of KOA. The purpose of this societal-endorsed position statement is to synthesize the current knowledge base for genicular artery embolization and review its biologic rationale, clinical evidence, technical considerations, safety profile, and evolving regulatory landscape.

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Cite

BibTeXRIS
BibTeX
@article{ahmed2026society,
  title = {{Society of Interventional Radiology Position Statement on Genicular Artery Embolization for Symptomatic Knee Osteoarthritis}},
  author = {Osman S. Ahmed and Bedros Taslakian and Yuji Okuno and Peter Minko and Jafar Golzarian and Sandeep Bagla and Marc R. Sapoval and Mateus P. Correa and Mark Little and Luke R. Wilkins and Joel A. Block and Brendon S. Ross and Sara Wallace and Magdalena Anițescu and Charles Ray and Siddharth A. Padia},
  journal = {Journal of Vascular and Interventional Radiology},
  year = {2026},
  month = may,
  doi = {10.1016/j.jvir.2026.108803},
  url = {https://doi.org/10.1016/j.jvir.2026.108803},
  note = {CC BY},
}
RIS
TY  - JOUR
TI  - Society of Interventional Radiology Position Statement on Genicular Artery Embolization for Symptomatic Knee Osteoarthritis
AU  - Osman S. Ahmed
AU  - Bedros Taslakian
AU  - Yuji Okuno
AU  - Peter Minko
AU  - Jafar Golzarian
AU  - Sandeep Bagla
AU  - Marc R. Sapoval
AU  - Mateus P. Correa
AU  - Mark Little
AU  - Luke R. Wilkins
AU  - Joel A. Block
AU  - Brendon S. Ross
AU  - Sara Wallace
AU  - Magdalena Anițescu
AU  - Charles Ray
AU  - Siddharth A. Padia
PY  - 2026
DA  - 2026/05/12
JO  - Journal of Vascular and Interventional Radiology
DO  - 10.1016/j.jvir.2026.108803
UR  - https://doi.org/10.1016/j.jvir.2026.108803
AB  - Knee osteoarthritis (KOA) is a prevalent musculoskeletal condition characterized by a significant therapeutic gap between the failure of conservative medical therapies and surgical arthroplasty. Contemporary evidence supports a model in which chronic synovitis and pathologic neoangiogenesis, closely coupled to perivascular nociceptive nerve growth, serve as significant contributors of pain and peripheral sensitization in KOA. Genicular artery embolization has emerged as a targeted, joint-preserving vascular intervention performed by interventional radiologists that directly addresses the inflammatory and neurovascular components of KOA. The purpose of this societal-endorsed position statement is to synthesize the current knowledge base for genicular artery embolization and review its biologic rationale, clinical evidence, technical considerations, safety profile, and evolving regulatory landscape.
SN  - 1051-0443
SN  - 1535-7732
ER  -