Impact of interventional embolization versus craniotomy and clipping on the neurological functional prognosis and quality of life in patients with intracranial aneurysms
- 1Department of Neurosurgery,Hunan Province Directly Affiliated Traditional Chinese Medicine Hospital,The FirstAffiliated Hospital of Hunan Traditional Chinese Medical College,Zhuzhou,Hunan 412000,China
Abstract
Objective To explore the application of propensity score matching(PSM)to balance confounding factors,and to compare the impacts of interventional embolization versus craniotomy and clipping on perioperative indicators,neurological functional prognosis,quality of life,and complications in patients with intracranial aneurysms (IA).Methods By retrospective cohort study,the clinical data of 98 patients with IA admitted to the Department of Neurosurgery,Hunan Province Directly Affiliated Traditional Chinese Medicine Hospital from July 2020 to July 2023 were selected,including 62 cases in the interventional embolization group(embolization group)and 36 cases in the craniotomy and clipping group(clipping group). Through PSM matching,32 effective pairs were finally obtained. The perioperative indicators,postoperative complications,neurological function prognosis［National Institutes of Health Stroke Scale(NIHSS),Glasgow Outcome Scale Extended(GOSE)］,quality of life［36-Item Short Form Health Survey(SF - 36),Activities of Daily Living Scale(ADL)］and aneurysm recurrence were compared between the two groups.Results Compared with the clipping group,the embolization group had shorter operation time and hospital stay,less intraoperative blood loss,but higher hospitalization cost(P<0.05). At 1,6 and 12 months after operation,the NIHSS scores of the embolization group were lower than those of the clipping group(P<0.05). The rate of favorable prognosis(GOSE score of 5)in the embolization group was significantly higher than that in the clipping group(93.75% vs 75.00%,χ2=4.270,P=0.039). At 1,6 and 12 months after operation,the total score of SF-36 scale and ADL score of the embolization group were higher than those of the clipping group(P<0.05). There was no statistically significant difference in the incidence of hydrocephalus,cerebral infarction,cerebral vasospasm and focal neurological dysfunction between the two groups within 30 days after operation(P>0.05). At 12 months after operation,there was no statistically significant difference in the recurrence rate between the embolization group and the clipping group(6.25% vs 9.38% ,χ2=0,P=1.000). Conclusion After balancing confounding factors through PSM,interventional embolization therapy demonstrates superiority over craniotomy and clipping in promoting neurological function recovery,and enhancing quality of life. It can be considered the preferred option for patients meeting interventional indications.
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BibTeX
@article{zaiqing2026impact,
title = {{Impact of interventional embolization versus craniotomy and clipping on the neurological functional prognosis and quality of life in patients with intracranial aneurysms}},
author = {BIN Zaiqing and TANG Qiyong and YIN Dianmin},
journal = {Zhongguo linchuang yanjiu},
year = {2026},
month = oct,
doi = {10.13429/j.cnki.cjcr.2026.10.011},
url = {https://doi.org/10.13429/j.cnki.cjcr.2026.10.011},
note = {CC BY-NC-ND},
}
RIS
TY - JOUR
TI - Impact of interventional embolization versus craniotomy and clipping on the neurological functional prognosis and quality of life in patients with intracranial aneurysms
AU - BIN Zaiqing
AU - TANG Qiyong
AU - YIN Dianmin
PY - 2026
DA - 2026/10/26
JO - Zhongguo linchuang yanjiu
DO - 10.13429/j.cnki.cjcr.2026.10.011
UR - https://doi.org/10.13429/j.cnki.cjcr.2026.10.011
AB - Objective To explore the application of propensity score matching(PSM)to balance confounding factors,and to compare the impacts of interventional embolization versus craniotomy and clipping on perioperative indicators,neurological functional prognosis,quality of life,and complications in patients with intracranial aneurysms (IA).Methods By retrospective cohort study,the clinical data of 98 patients with IA admitted to the Department of Neurosurgery,Hunan Province Directly Affiliated Traditional Chinese Medicine Hospital from July 2020 to July 2023 were selected,including 62 cases in the interventional embolization group(embolization group)and 36 cases in the craniotomy and clipping group(clipping group). Through PSM matching,32 effective pairs were finally obtained. The perioperative indicators,postoperative complications,neurological function prognosis［National Institutes of Health Stroke Scale(NIHSS),Glasgow Outcome Scale Extended(GOSE)］,quality of life［36-Item Short Form Health Survey(SF - 36),Activities of Daily Living Scale(ADL)］and aneurysm recurrence were compared between the two groups.Results Compared with the clipping group,the embolization group had shorter operation time and hospital stay,less intraoperative blood loss,but higher hospitalization cost(P<0.05). At 1,6 and 12 months after operation,the NIHSS scores of the embolization group were lower than those of the clipping group(P<0.05). The rate of favorable prognosis(GOSE score of 5)in the embolization group was significantly higher than that in the clipping group(93.75% vs 75.00%,χ2=4.270,P=0.039). At 1,6 and 12 months after operation,the total score of SF-36 scale and ADL score of the embolization group were higher than those of the clipping group(P<0.05). There was no statistically significant difference in the incidence of hydrocephalus,cerebral infarction,cerebral vasospasm and focal neurological dysfunction between the two groups within 30 days after operation(P>0.05). At 12 months after operation,there was no statistically significant difference in the recurrence rate between the embolization group and the clipping group(6.25% vs 9.38% ,χ2=0,P=1.000). Conclusion After balancing confounding factors through PSM,interventional embolization therapy demonstrates superiority over craniotomy and clipping in promoting neurological function recovery,and enhancing quality of life. It can be considered the preferred option for patients meeting interventional indications.
SN - 1674-8182
ER -