EVALUATING THE ASSOCIATION OF CANCER-RELATED RISK FACTORS WITH MULTISYSTEM HEALTH: INSIGHTS INTO FERTILITY, CARDIOVASCULAR, AND RENAL INDICATORS
- 1General Practitioner, Elova Hospitals, 27, 5th Cross, Lalbagh Main Rd, Sudhama Nagar, Bengaluru -560027
Abstract
Cancer-related lifestyle and metabolic risk factors, including smoking, alcohol use, physical inactivity, and obesity, are widely recognized for their role in disease development. However, their association with multisystem health outcomes, particularly cardiovascular, renal, and reproductive indicators, remains less clearly characterized in general populations. This cross-sectional study utilized secondary data from the National Health and Nutrition Examination Survey (NHANES). Adult participants aged ≥20 years with complete demographic, clinical, laboratory, and questionnaire data were included (n = 5,588). Cancer-related risk factors were assessed, and outcomes included cardiovascular, renal, and fertility indicators. Statistical analyses included descriptive statistics, group comparisons, and multivariable logistic regression to estimate adjusted associations. A high prevalence of cancer-related risk factors was observed, including smoking, alcohol use, physical inactivity, and obesity. Multisystem abnormalities such as elevated blood pressure, dyslipidemia, and renal impairment were common. Obesity was consistently associated with cardiovascular outcomes and infertility. Smoking was associated with cardiovascular and renal indicators, while physical inactivity was associated with renal impairment. Alcohol use was not significantly associated with outcomes after adjustment. Cancer-related lifestyle and metabolic risk factors were associated with variations in cardiovascular, renal, and reproductive indicators within a general adult population. These findings highlight the presence of overlapping risk factors and multisystem health measures without extending beyond observed associations.
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BibTeX
@article{rajendran2026evaluating,
title = {{EVALUATING THE ASSOCIATION OF CANCER-RELATED RISK FACTORS WITH MULTISYSTEM HEALTH: INSIGHTS INTO FERTILITY, CARDIOVASCULAR, AND RENAL INDICATORS}},
author = {Latha Kiran Krishna Rajendran},
journal = {Research},
year = {2026},
month = jun,
doi = {10.5281/zenodo.20767373},
url = {https://doi.org/10.5281/zenodo.20767373},
note = {CC BY},
}
RIS
TY - JOUR
TI - EVALUATING THE ASSOCIATION OF CANCER-RELATED RISK FACTORS WITH MULTISYSTEM HEALTH: INSIGHTS INTO FERTILITY, CARDIOVASCULAR, AND RENAL INDICATORS
AU - Latha Kiran Krishna Rajendran
PY - 2026
DA - 2026/06/19
JO - Research
DO - 10.5281/zenodo.20767373
UR - https://doi.org/10.5281/zenodo.20767373
AB - Cancer-related lifestyle and metabolic risk factors, including smoking, alcohol use, physical inactivity, and obesity, are widely recognized for their role in disease development. However, their association with multisystem health outcomes, particularly cardiovascular, renal, and reproductive indicators, remains less clearly characterized in general populations. This cross-sectional study utilized secondary data from the National Health and Nutrition Examination Survey (NHANES). Adult participants aged ≥20 years with complete demographic, clinical, laboratory, and questionnaire data were included (n = 5,588). Cancer-related risk factors were assessed, and outcomes included cardiovascular, renal, and fertility indicators. Statistical analyses included descriptive statistics, group comparisons, and multivariable logistic regression to estimate adjusted associations. A high prevalence of cancer-related risk factors was observed, including smoking, alcohol use, physical inactivity, and obesity. Multisystem abnormalities such as elevated blood pressure, dyslipidemia, and renal impairment were common. Obesity was consistently associated with cardiovascular outcomes and infertility. Smoking was associated with cardiovascular and renal indicators, while physical inactivity was associated with renal impairment. Alcohol use was not significantly associated with outcomes after adjustment. Cancer-related lifestyle and metabolic risk factors were associated with variations in cardiovascular, renal, and reproductive indicators within a general adult population. These findings highlight the presence of overlapping risk factors and multisystem health measures without extending beyond observed associations.
SN - 2407-9529
ER -