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Peer-reviewedCC BYEJHaem

Cyclosporine A and Romiplostim as a Bridging Therapy to Curative Surgery in Aplastic Anemia Complicated by Gastric Cancer: A Case Report.

  • Noriharu Nakagawa1
  • Masahide Yamazaki1
  • Kohei Hosokawa2
  1. 1Department of Hematology Keiju Medical Center Nanao Japan.
  2. 2Department of Hematology Faculty of Medicine Institute of Medical Pharmaceutical and Health Sciences Kanazawa University Kanazawa Japan.
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Abstract

We present a case of aplastic anemia (AA) complicated with gastric cancer that was successfully treated with cyclosporine A (CsA) and romiplostim (ROMI) as a bridging therapy before curative surgery. This patient had untreated gastric cancer at the time of AA diagnosis, and surgery was difficult because of thrombocytopenia. However, CsA and ROMI were effective, resulting in a rapid increase in the platelet count, thereby making surgery for gastric cancer possible. CsA and ROMI as a bridging therapy to curative surgery may therefore represent a feasible treatment option in patients with AA complicated by malignant tumors. Trial Registration: The authors have confirmed clinical trial registration is not needed for this submission.

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Cite

BibTeXRIS
BibTeX
@article{nakagawa2026cyclosporine,
  title = {{Cyclosporine A and Romiplostim as a Bridging Therapy to Curative Surgery in Aplastic Anemia Complicated by Gastric Cancer: A Case Report.}},
  author = {Noriharu Nakagawa and Masahide Yamazaki and Kohei Hosokawa},
  journal = {EJHaem},
  year = {2026},
  month = oct,
  doi = {10.1002/jha2.70440},
  url = {https://europepmc.org/article/MED/42909854},
  note = {CC BY},
}
RIS
TY  - JOUR
TI  - Cyclosporine A and Romiplostim as a Bridging Therapy to Curative Surgery in Aplastic Anemia Complicated by Gastric Cancer: A Case Report.
AU  - Noriharu Nakagawa
AU  - Masahide Yamazaki
AU  - Kohei Hosokawa
PY  - 2026
DA  - 2026/10/21
JO  - EJHaem
DO  - 10.1002/jha2.70440
UR  - https://europepmc.org/article/MED/42909854
AB  - We present a case of aplastic anemia (AA) complicated with gastric cancer that was successfully treated with cyclosporine A (CsA) and romiplostim (ROMI) as a bridging therapy before curative surgery. This patient had untreated gastric cancer at the time of AA diagnosis, and surgery was difficult because of thrombocytopenia. However, CsA and ROMI were effective, resulting in a rapid increase in the platelet count, thereby making surgery for gastric cancer possible. CsA and ROMI as a bridging therapy to curative surgery may therefore represent a feasible treatment option in patients with AA complicated by malignant tumors. Trial Registration: The authors have confirmed clinical trial registration is not needed for this submission.
SN  - 2688-6146
ER  -