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Peer-reviewedCC BYCureus

Severe Hyponatremia as an Early Manifestation of Peritransplant Abscess After Living Donor Kidney Transplantation: A Case Report.

  • Aaron Huang1
  • Rachael Molina2
  • Navdeep Kaur3
  • Dawn Francisquini1
  • Adam M Kressel1
  1. 1Department of Urology, State University of New York at Stony Brook, Stony Brook, USA.
  2. 2Renaissance School of Medicine, State University of New York at Stony Brook, Stony Brook, USA.
  3. 3Department of Nephrology, State University of New York at Stony Brook, Stony Brook, USA.
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Abstract

Electrolyte abnormalities are common after kidney transplantation, but severe hyponatremia as an early sign of occult peritransplant infection is rare. A 68-year-old woman underwent living unrelated kidney transplantation and was discharged on postoperative day 4 with a drain in place. On postoperative day 8, she developed acute kidney injury and profound hyponatremia, with a serum sodium level of 109 mmol/L, despite only mild fatigue and no fever, abdominal pain, allograft tenderness, or wound symptoms. Sodium improved with hypertonic saline, nutritional support, and fluid restriction. On postoperative day 13, she developed fever; computed tomography revealed a 16-cm peritransplant abscess, and drainage grew Escherichia coli. This case highlights severe unexplained hyponatremia as a potential early manifestation of occult infectious or surgical complications after kidney transplantation.

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Cite

BibTeXRIS
BibTeX
@article{huang2026severe,
  title = {{Severe Hyponatremia as an Early Manifestation of Peritransplant Abscess After Living Donor Kidney Transplantation: A Case Report.}},
  author = {Aaron Huang and Rachael Molina and Navdeep Kaur and Dawn Francisquini and Adam M Kressel},
  journal = {Cureus},
  year = {2026},
  month = sep,
  doi = {10.7759/cureus.116505},
  url = {https://europepmc.org/article/MED/42898987},
  note = {CC BY},
}
RIS
TY  - JOUR
TI  - Severe Hyponatremia as an Early Manifestation of Peritransplant Abscess After Living Donor Kidney Transplantation: A Case Report.
AU  - Aaron Huang
AU  - Rachael Molina
AU  - Navdeep Kaur
AU  - Dawn Francisquini
AU  - Adam M Kressel
PY  - 2026
DA  - 2026/09/18
JO  - Cureus
DO  - 10.7759/cureus.116505
UR  - https://europepmc.org/article/MED/42898987
AB  - Electrolyte abnormalities are common after kidney transplantation, but severe hyponatremia as an early sign of occult peritransplant infection is rare. A 68-year-old woman underwent living unrelated kidney transplantation and was discharged on postoperative day 4 with a drain in place. On postoperative day 8, she developed acute kidney injury and profound hyponatremia, with a serum sodium level of 109 mmol/L, despite only mild fatigue and no fever, abdominal pain, allograft tenderness, or wound symptoms. Sodium improved with hypertonic saline, nutritional support, and fluid restriction. On postoperative day 13, she developed fever; computed tomography revealed a 16-cm peritransplant abscess, and drainage grew Escherichia coli. This case highlights severe unexplained hyponatremia as a potential early manifestation of occult infectious or surgical complications after kidney transplantation.
SN  - 2168-8184
ER  -