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Peer-reviewedCC BY-NC-NDEJNMMI reports

Expanding role of nuclear medicine in cardiac amyloidosis: insights from the EJNMMI collection.

  • Mahdi Zirakchian Zadeh1
  • Medhat M Osman2
  1. 1Division of Nuclear Medicine, Department of Radiology, SSM Health Saint Louis University Hospital, St. Louis, MO, USA. [email protected].
  2. 2Division of Nuclear Medicine, Department of Radiology, SSM Health Saint Louis University Hospital, St. Louis, MO, USA.
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Abstract

Recent advances in nuclear medicine are reshaping the evaluation of cardiac amyloidosis, as highlighted by the recent collection published in EJNMMI (collection link: https://link.springer.com/collections/igfdhcddjg). This commentary summarizes key insights from these studies, emphasizing the evolving shift from conventional diagnostic imaging toward a more integrated and comprehensive approach. Emerging developments include novel amyloid PET tracers, improved diagnostic accuracy with SPECT/CT, multimodality imaging strategies, and enhanced assessment of systemic disease burden extending beyond the left ventricle. There is also growing interest in longitudinal monitoring, pre-symptomatic detection, and the role of artificial intelligence. Together, these advances position nuclear medicine as an essential tool for disease characterization, risk stratification, and treatment assessment.

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Cite

BibTeXRIS
BibTeX
@article{zadeh2026expanding,
  title = {{Expanding role of nuclear medicine in cardiac amyloidosis: insights from the EJNMMI collection.}},
  author = {Mahdi Zirakchian Zadeh and Medhat M Osman},
  journal = {EJNMMI reports},
  year = {2026},
  month = oct,
  doi = {10.1186/s41824-026-00326-3},
  url = {https://europepmc.org/article/MED/42894083},
  note = {CC BY-NC-ND},
}
RIS
TY  - JOUR
TI  - Expanding role of nuclear medicine in cardiac amyloidosis: insights from the EJNMMI collection.
AU  - Mahdi Zirakchian Zadeh
AU  - Medhat M Osman
PY  - 2026
DA  - 2026/10/19
JO  - EJNMMI reports
DO  - 10.1186/s41824-026-00326-3
UR  - https://europepmc.org/article/MED/42894083
AB  - Recent advances in nuclear medicine are reshaping the evaluation of cardiac amyloidosis, as highlighted by the recent collection published in EJNMMI (collection link: https://link.springer.com/collections/igfdhcddjg). This commentary summarizes key insights from these studies, emphasizing the evolving shift from conventional diagnostic imaging toward a more integrated and comprehensive approach. Emerging developments include novel amyloid PET tracers, improved diagnostic accuracy with SPECT/CT, multimodality imaging strategies, and enhanced assessment of systemic disease burden extending beyond the left ventricle. There is also growing interest in longitudinal monitoring, pre-symptomatic detection, and the role of artificial intelligence. Together, these advances position nuclear medicine as an essential tool for disease characterization, risk stratification, and treatment assessment.
SN  - 3005-074X
ER  -