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Peer-reviewedCC BY 3.0Chemical Communications (Cambridge, England)

Liposome-based responsive MRI contrast agents

  • Anna M. Duncan1
  • Connor M. Ellis1
  • James P. Smith1
  • Jason J. Davis1
  1. 1Department of Chemistry, University of Oxford South Parks Road Oxford OX1 3QZ UK +44 01865 275 914 +44 01865 275 914
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Abstract

Liposomes present a promising architecture for the design of responsive MRI CAs. The ability to co-encapsulate diagnostic and therapeutic payloads further allows for (targeted) imaging and treatment of disease in vivo. Tuneable control over embedded motifs, or modification of the bilayer phospholipids themselves, can support a programmable response to disease microenvironments. In this review we summarise the design and underpinning theoretical principles relevant to the production of next-generation diagnostically potent responsive liposome-based MRI CAs.

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Cite

BibTeXRIS
BibTeX
@article{duncan2026liposomebased,
  title = {{Liposome-based responsive MRI contrast agents}},
  author = {Anna M. Duncan and Connor M. Ellis and James P. Smith and Jason J. Davis},
  journal = {Chemical Communications (Cambridge, England)},
  year = {2026},
  month = oct,
  doi = {10.1039/d6cc05928g},
  url = {https://doi.org/10.1039/d6cc05928g},
  note = {CC BY 3.0},
}
RIS
TY  - JOUR
TI  - Liposome-based responsive MRI contrast agents
AU  - Anna M. Duncan
AU  - Connor M. Ellis
AU  - James P. Smith
AU  - Jason J. Davis
PY  - 2026
DA  - 2026/10/09
JO  - Chemical Communications (Cambridge, England)
DO  - 10.1039/d6cc05928g
UR  - https://doi.org/10.1039/d6cc05928g
AB  - Liposomes present a promising architecture for the design of responsive MRI CAs. The ability to co-encapsulate diagnostic and therapeutic payloads further allows for (targeted) imaging and treatment of disease in vivo. Tuneable control over embedded motifs, or modification of the bilayer phospholipids themselves, can support a programmable response to disease microenvironments. In this review we summarise the design and underpinning theoretical principles relevant to the production of next-generation diagnostically potent responsive liposome-based MRI CAs.
SN  - 1359-7345
SN  - 1364-548X
ER  -