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Peer-reviewedCC BY 4.0PLOS Biology

Better antibodies, better science

  • Johan Duchêne1
  1. 1Institute for Cardiovascular Prevention (IPEK), Ludwig-Maximilians-University (LMU), LMU Open Science Center (OSC), German Center for Cardiovascular Research (DZHK), Munich, Germany
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Abstract

Poorly validated antibodies generate misleading results and waste research resources. Two new studies in PLOS Biology quantify the ethical costs of this issue, examine why unvalidated antibodies are still used, and identify solutions to reduce their use.

Poorly validated antibodies generate misleading results and waste research resources. This Primer explores two new studies in PLOS Biology that quantify the ethical costs of this issue, examine why unvalidated antibodies are still used, and identify solutions to reduce their use.

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Cite

BibTeXRIS
BibTeX
@article{duchene2026better,
  title = {{Better antibodies, better science}},
  author = {Johan Duchêne},
  journal = {PLOS Biology},
  year = {2026},
  month = oct,
  doi = {10.1371/journal.pbio.3004001},
  url = {https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.3004001},
  note = {CC BY 4.0},
}
RIS
TY  - JOUR
TI  - Better antibodies, better science
AU  - Johan Duchêne
PY  - 2026
DA  - 2026/10/07
JO  - PLOS Biology
DO  - 10.1371/journal.pbio.3004001
UR  - https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.3004001
AB  - Poorly validated antibodies generate misleading results and waste research resources. Two new studies in PLOS Biology quantify the ethical costs of this issue, examine why unvalidated antibodies are still used, and identify solutions to reduce their use.  Poorly validated antibodies generate misleading results and waste research resources. This Primer explores two new studies in PLOS Biology that quantify the ethical costs of this issue, examine why unvalidated antibodies are still used, and identify solutions to reduce their use.
SN  - 1545-7885
ER  -