"Remembering to Remember: The Road Less Traveled in Alzheimer's Disease — A Testable Framework for Retrieval Architecture, Anticipatory Preparation, and Preservation of Personhood."
Abstract
Pre-Prin
This theoretical research paper proposes a testable framework for improving functional memory access in cognitive aging and Alzheimer's disease through anticipatory retrieval preparation.
The framework distinguishes the storage of information from the ability to initiate and successfully retrieve information. It introduces the Anticipatory Retrieval Set (ARS), a structured cognitive preparation process, and the Fixed Predictable Retrieval Routine (FPRR), designed to promote consistent retrieval preparation before memory demands arise.
Central to the proposal is the Pre-Error Principle: preparing the individual for successful retrieval before an error occurs, rather than relying primarily on correction after unsuccessful recall. The framework also examines production before perceptual confirmation, repeated successful retrieval, reduced external prompting, and increasing self-initiation.
The paper proposes controlled experimental comparisons between conventional retrieval practice and equivalent retrieval practice supplemented by anticipatory preparation. Proposed outcomes include independent recall, retrieval latency, retention, transfer to new information, cue dependence, and self-initiated remembering.
The central hypothesis is that anticipatory retrieval preparation may become an independently trainable component of remembering, potentially supporting functional independence and preservation of personhood.
This is a theoretical, hypothesis-generating research contribution. It does not claim to cure Alzheimer's disease, reverse neurodegeneration, or establish clinical efficacy. Its purpose is to identify a scientifically testable approach to improving functional memory access.
Related
- Preparation of chitosan oligosaccharide-porphyrin conjugate and its photodynamic preservation effect on Litopenaeus vannamei.
- A Novel Arthroscopic Curette Microphone for Cartilage Defect Preparation in Joint Preservation Surgery: Proof-of-Concept and Tissue-Specific Debridement Audio Features.
- Exceptional preservation in cherts reveals complex cuticular architecture in one of the earliest Cambrian ecdysozoans
- Pore architecture governs tannic acid release from porous Poria cocos polysaccharide beads for headspace antioxidant preservation of fruit
- Preparation of a Lotus-Leaf-Inspired PVA-Grape Seed Extract Biomimetic Gel Film and Its Application in Active Packaging for the Postharvest Preservation of Agaricus bisporus.
BibTeX
@misc{maricic2026remembering,
title = {{"Remembering to Remember: The Road Less Traveled in Alzheimer's Disease — A Testable Framework for Retrieval Architecture, Anticipatory Preparation, and Preservation of Personhood."}},
author = {Nick Maricic and Nick Maricic},
howpublished = {Zenodo},
year = {2026},
month = oct,
doi = {10.5281/zenodo.23604899},
url = {https://zenodo.org/records/23604899},
note = {CC BY 4.0},
}
RIS
TY - UNPB
TI - "Remembering to Remember: The Road Less Traveled in Alzheimer's Disease — A Testable Framework for Retrieval Architecture, Anticipatory Preparation, and Preservation of Personhood."
AU - Nick Maricic
AU - Nick Maricic
PY - 2026
DA - 2026/10/23
PB - Zenodo
DO - 10.5281/zenodo.23604899
UR - https://zenodo.org/records/23604899
AB - Pre-Prin This theoretical research paper proposes a testable framework for improving functional memory access in cognitive aging and Alzheimer's disease through anticipatory retrieval preparation. The framework distinguishes the storage of information from the ability to initiate and successfully retrieve information. It introduces the Anticipatory Retrieval Set (ARS), a structured cognitive preparation process, and the Fixed Predictable Retrieval Routine (FPRR), designed to promote consistent retrieval preparation before memory demands arise. Central to the proposal is the Pre-Error Principle: preparing the individual for successful retrieval before an error occurs, rather than relying primarily on correction after unsuccessful recall. The framework also examines production before perceptual confirmation, repeated successful retrieval, reduced external prompting, and increasing self-initiation. The paper proposes controlled experimental comparisons between conventional retrieval practice and equivalent retrieval practice supplemented by anticipatory preparation. Proposed outcomes include independent recall, retrieval latency, retention, transfer to new information, cue dependence, and self-initiated remembering. The central hypothesis is that anticipatory retrieval preparation may become an independently trainable component of remembering, potentially supporting functional independence and preservation of personhood. This is a theoretical, hypothesis-generating research contribution. It does not claim to cure Alzheimer's disease, reverse neurodegeneration, or establish clinical efficacy. Its purpose is to identify a scientifically testable approach to improving functional memory access.
ER -