Peer-reviewedCC BYFrontiers in pharmacology
Gastrodin alleviates mild cognitive impairment and Alzheimer’s disease via candidate targeting of ACHE, S1PR5, SERPINE1, and TOP2A: an integrative computational and cellular study
5 affiliations
- 1Innovation Institute of Integrated Traditional Chinese and Western Medicine, Institute of Brain Science and Brain-inspired Research, Shandong First Medical University & Shandong Academy of Medical Sciences , ,
- 2Traditional Chinese Medicine (TCM) Rehabilitation Department, Danjiangkou Liuliping Central Health Center , ,
- 3Hubei Key Laboratory of Embryonic Stem Cell Research, Department of Human Anatomy, Hubei University of Medicine , ,
- 4Taihe Hospital, Hubei University of Medicine , ,
- 5Department of Neurosurgery, Shengli Oilfield Central Hospital , ,
Related
- The ameliorative effects of gastrodin on cognitive impairment in STZ-treated mice are associated with the modulation of hippocampal neurogenesis-related proteins and inhibition of the AGEs–RAGE axis
- Prediction of cognitive impairment in Parkinson’s disease using TabPFN: an integrative analysis of clinical data, longitudinal trajectories, and lipidomics
- Endoplasmic Reticulum Autophagy Enhancement Alleviates Synaptic Plasticity Dysfunction and Ameliorates Cognitive Impairment in SAE Mice by Relieving STING‐Associated Inhibition of PKM2 Activity
- Integrative approaches to acupuncture therapies for post-stroke mild cognitive impairment: a systematic review and network meta-analysis
- EEG-centred computational biomarkers and complementary physiological signals for mild cognitive impairment and early Alzheimer’s disease: A systematic review 2005–2025
BibTeX
@article{wang2026gastrodin,
title = {{Gastrodin alleviates mild cognitive impairment and Alzheimer’s disease via candidate targeting of ACHE, S1PR5, SERPINE1, and TOP2A: an integrative computational and cellular study}},
author = {Yu Wang and Meng-xi Liu and Jia-lu Zhu and Gui-xian Li and Hong Yu and Cong-hui Wang and Qiang Zong and Wen-sheng Wang},
journal = {Frontiers in pharmacology},
year = {2026},
month = oct,
url = {https://europepmc.org/article/PMC/PMC13658492},
note = {CC BY},
}
RIS
TY - JOUR
TI - Gastrodin alleviates mild cognitive impairment and Alzheimer’s disease via candidate targeting of ACHE, S1PR5, SERPINE1, and TOP2A: an integrative computational and cellular study
AU - Yu Wang
AU - Meng-xi Liu
AU - Jia-lu Zhu
AU - Gui-xian Li
AU - Hong Yu
AU - Cong-hui Wang
AU - Qiang Zong
AU - Wen-sheng Wang
PY - 2026
DA - 2026/10/16
JO - Frontiers in pharmacology
UR - https://europepmc.org/article/PMC/PMC13658492
SN - 1663-9812
ER -