Peer-reviewedCC BY-NC-NDUrology case reports
Reconstructing the irradiated urethra: Double-Faced buccal mucosal graft urethroplasty after treatment of primary urethral cancer.
- 1University of California, Irvine. School of Medicine, Department of Urology, Reconstructive Division, California, United States.
Abstract
We report the case of a 42-year-old man who developed a 6 cm near-obliterative bulbar and membranous urethral stricture after radiation for primary urethral squamous cell carcinoma. Reconstruction was performed using a combination of membranous scar excision and a double-faced buccal mucosal graft urethroplasty. Cystourethroscopy at 4 months demonstrated a widely patent urethra, and the AUA Symptom Score improved from 25 before surgery to 3 at three years. Urethroplasty after radiation for urethral cancer has not been previously well described. This case suggests single-stage urethroplasty is a feasible option for reconstruction of urethral strictures after radiation for urethral cancer.
Related
- Staged buccal mucosa graft urethroplasty in the treatment of male urethral war injuries
- Early Outcomes of Dorsal Onlay Buccal Mucosal Graft Urethroplasty for Female Urethral Stricture Disease: A Single-Center Experience
- Understanding global practice patterns in bulbar urethral reconstruction to inform urethroplasty training
- Post-Treatment Response and Safety of Stem Cell-Based Urethral Injection Therapy for Female Stress Urinary Incontinence: A Systematic Review and Meta-Analysis
- Association between preoperative hemoglobin, albumin, lymphocyte, and platelet (HALP) score and stricture recurrence after urethroplasty
BibTeX
@article{behtash2026reconstructing,
title = {{Reconstructing the irradiated urethra: Double-Faced buccal mucosal graft urethroplasty after treatment of primary urethral cancer.}},
author = {Negar Behtash and Sikai Song and Zhina Sadeghi and Keith Rourke and Joel Gelman},
journal = {Urology case reports},
year = {2026},
month = oct,
doi = {10.1016/j.eucr.2026.103653},
url = {https://europepmc.org/article/MED/42997819},
note = {CC BY-NC-ND},
}
RIS
TY - JOUR
TI - Reconstructing the irradiated urethra: Double-Faced buccal mucosal graft urethroplasty after treatment of primary urethral cancer.
AU - Negar Behtash
AU - Sikai Song
AU - Zhina Sadeghi
AU - Keith Rourke
AU - Joel Gelman
PY - 2026
DA - 2026/10/27
JO - Urology case reports
DO - 10.1016/j.eucr.2026.103653
UR - https://europepmc.org/article/MED/42997819
AB - We report the case of a 42-year-old man who developed a 6 cm near-obliterative bulbar and membranous urethral stricture after radiation for primary urethral squamous cell carcinoma. Reconstruction was performed using a combination of membranous scar excision and a double-faced buccal mucosal graft urethroplasty. Cystourethroscopy at 4 months demonstrated a widely patent urethra, and the AUA Symptom Score improved from 25 before surgery to 3 at three years. Urethroplasty after radiation for urethral cancer has not been previously well described. This case suggests single-stage urethroplasty is a feasible option for reconstruction of urethral strictures after radiation for urethral cancer.
SN - 2214-4420
ER -