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Peer-reviewedCC BYJournal of patient-reported outcomes

Psychometric properties of the Functional Assessment of Cancer Therapy-Lung (FACT-L) scale to measure health-related quality of life.

  • Jose A Carreno1,2
  • Luis Fontibón3
  • Carlos Carvajal3
  • Jorge Rugeles4
  • Alicia Quiroga5
  • Ricardo Buitrago3,6
  • Jose Venegas7
  • Ricardo Sanchez8
8 affiliations
  1. 1Instituto Nacional de Cancerología, Bogotá, Colombia. [email protected].
  2. 2National University of Colombia, Bogotá, Colombia. [email protected].
  3. 3Instituto Nacional de Cancerología, Bogotá, Colombia.
  4. 4Clínica IMAT Oncomédica Auna, Montería, Colombia.
  5. 5Hospital Pablo Tobon Uribe, Medellín, Colombia.
  6. 6Clinica de Marly, Bogotá, Colombia.
  7. 7Hospital Alma Máter de Antioquia, Medellín, Colombia.
  8. 8National University of Colombia, Bogotá, Colombia.
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Abstract

Purpose

To validate the Functional Assessment of Cancer Therapy-Lung (FACT-L) scale and assess its psychometric properties in patients with lung cancer in Colombia.Methods

The analysis included exploratory and confirmatory factor analysis, internal consistency (248 patients diagnosed with lung cancer), test-retest reliability (56 patients evaluated at two different time points), discriminant, convergent and divergent validity.Results

Factor analysis revealed a two-dimensional structure within the lung cancer-specific subscale (LCS). Cronbach's alpha was 0.91, ω McDonald 0.92 and Guttman's λ2 0.92 for the FACT-L. Lin's concordance correlation coefficient indicated test-retest reliability (0.8, 95% CI: 0.69-0.88) adequate for uses of the tool. Convergent validity assessed through Spearman's rho correlation coefficient was 0.64 (95% CI: 0.56-0.71, p < 0.001). In divergent validity, the result was a rho - 0.432 (P = < 0.001); in discriminant validity was a rho of 0.141 (P = 0.027).Conclusion

Internal consistency analyses demonstrated strong inter-item correlations and high homogeneity. Discriminant, convergent, and divergent validity support the scale's ability to distinguish between conceptually distinct constructs, and test-retest reliability confirmed temporal stability. The FACT-L scale is a valid and reliable instrument for assessing health-related quality of life in patients with lung cancer in the Colombian context.

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Cite

BibTeXRIS
BibTeX
@article{carreno2026psychometric,
  title = {{Psychometric properties of the Functional Assessment of Cancer Therapy-Lung (FACT-L) scale to measure health-related quality of life.}},
  author = {Jose A Carreno and Luis Fontibón and Carlos Carvajal and Jorge Rugeles and Alicia Quiroga and Ricardo Buitrago and Jose Venegas and Ricardo Sanchez},
  journal = {Journal of patient-reported outcomes},
  year = {2026},
  month = jul,
  doi = {10.1186/s41687-026-01164-4},
  url = {https://europepmc.org/article/MED/42967976},
  note = {CC BY},
}
RIS
TY  - JOUR
TI  - Psychometric properties of the Functional Assessment of Cancer Therapy-Lung (FACT-L) scale to measure health-related quality of life.
AU  - Jose A Carreno
AU  - Luis Fontibón
AU  - Carlos Carvajal
AU  - Jorge Rugeles
AU  - Alicia Quiroga
AU  - Ricardo Buitrago
AU  - Jose Venegas
AU  - Ricardo Sanchez
PY  - 2026
DA  - 2026/07/31
JO  - Journal of patient-reported outcomes
DO  - 10.1186/s41687-026-01164-4
UR  - https://europepmc.org/article/MED/42967976
AB  - Purpose  To validate the Functional Assessment of Cancer Therapy-Lung (FACT-L) scale and assess its psychometric properties in patients with lung cancer in Colombia.Methods  The analysis included exploratory and confirmatory factor analysis, internal consistency (248 patients diagnosed with lung cancer), test-retest reliability (56 patients evaluated at two different time points), discriminant, convergent and divergent validity.Results  Factor analysis revealed a two-dimensional structure within the lung cancer-specific subscale (LCS). Cronbach's alpha was 0.91, ω McDonald 0.92 and Guttman's λ2 0.92 for the FACT-L. Lin's concordance correlation coefficient indicated test-retest reliability (0.8, 95% CI: 0.69-0.88) adequate for uses of the tool. Convergent validity assessed through Spearman's rho correlation coefficient was 0.64 (95% CI: 0.56-0.71, p < 0.001). In divergent validity, the result was a rho - 0.432 (P = < 0.001); in discriminant validity was a rho of 0.141 (P = 0.027).Conclusion  Internal consistency analyses demonstrated strong inter-item correlations and high homogeneity. Discriminant, convergent, and divergent validity support the scale's ability to distinguish between conceptually distinct constructs, and test-retest reliability confirmed temporal stability. The FACT-L scale is a valid and reliable instrument for assessing health-related quality of life in patients with lung cancer in the Colombian context.
SN  - 2509-8020
ER  -