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Peer-reviewedLicence not statedCell

AI-driven discovery of GPNMB CAR T cells as a multi-cancer therapy

  • Daniel J. Baker
  • Leon Merlin Frommer1
  • Uğur Uslu2
  • Kisha K. Patel3
  • Daniel Zhu3
  • Nils W. Engel3
  • James M. George4
  • Wencao Zhao5
  • Samuel I. Kim3
  • Lisa Sun3
  • Christopher Roselle3
  • Philipp C. Rommel3
5 more authors
  • Regina M. Young3
  • Jonathan A. Epstein
  • Sikander Hayat6
  • Zoltan Arany7
  • Carl H. June8
8 affiliations
  1. 1Department of Medicine 2, RWTH Aachen University, Medical Faculty, Aachen, Germany
  2. 2Center for Cellular Immunotherapies, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104, USA; Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104, USA; Department of Dermatology, Venereology and Allergology, University Hospital Würzburg, 97080 Würzburg, Germany
  3. 3Center for Cellular Immunotherapies, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104, USA; Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104, USA
  4. 4Michigan Center for Translational Pathology, University of Michigan, Ann Arbor, MI, USA
  5. 5Cardiovascular Institute, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA
  6. 6Department of Medicine 2, RWTH Aachen University, Medical Faculty, Aachen, Germany; Cardiovascular Research Institute, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA; Windreich Department of Artificial Intelligence and Human Health, Icahn School of Medicine at Mount Sinai, New York, NY, USA. Electronic address: [email protected]
  7. 7Cardiovascular Institute, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA; Department of Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA; Department of Physiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA. Electronic address: [email protected]
  8. 8Center for Cellular Immunotherapies, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104, USA; Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104, USA; Parker Institute for Cancer Immunotherapy at University of Pennsylvania, Philadelphia, PA 19104, USA. Electronic address: [email protected]
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Cite

BibTeXRIS
BibTeX
@article{baker2026aidriven,
  title = {{AI-driven discovery of GPNMB CAR T cells as a multi-cancer therapy}},
  author = {Daniel J. Baker and Leon Merlin Frommer and Uğur Uslu and Kisha K. Patel and Daniel Zhu and Nils W. Engel and James M. George and Wencao Zhao and Samuel I. Kim and Lisa Sun and Christopher Roselle and Philipp C. Rommel and Regina M. Young and Jonathan A. Epstein and Sikander Hayat and Zoltan Arany and Carl H. June},
  journal = {Cell},
  year = {2026},
  month = jun,
  doi = {10.1016/j.cell.2026.06.002},
  url = {https://pmc.ncbi.nlm.nih.gov/articles/PMC13428302/},
}
RIS
TY  - JOUR
TI  - AI-driven discovery of GPNMB CAR T cells as a multi-cancer therapy
AU  - Daniel J. Baker
AU  - Leon Merlin Frommer
AU  - Uğur Uslu
AU  - Kisha K. Patel
AU  - Daniel Zhu
AU  - Nils W. Engel
AU  - James M. George
AU  - Wencao Zhao
AU  - Samuel I. Kim
AU  - Lisa Sun
AU  - Christopher Roselle
AU  - Philipp C. Rommel
AU  - Regina M. Young
AU  - Jonathan A. Epstein
AU  - Sikander Hayat
AU  - Zoltan Arany
AU  - Carl H. June
PY  - 2026
DA  - 2026/06/01
JO  - Cell
DO  - 10.1016/j.cell.2026.06.002
UR  - https://pmc.ncbi.nlm.nih.gov/articles/PMC13428302/
SN  - 0092-8674
SN  - 1097-4172
ER  -