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Peer-reviewedCC BY 4.0BMJ Open

Implementing a patient-centred and evidence-based intervention to reduce BEnzodiazepine and sedative-hypnotic use to improve patient SAFEty and quality of care (BE-SAFE): study protocol of a cluster randomised controlled trial

  • Maria-Lisa Kleinert1,2
  • Sarah Atighetchi1,2
  • Julia Isabel Beck1,2
  • Lucy Bolt1,2
  • Odile Stalder3
  • Rita Romskaug4
  • Enrico Callegari4,5
  • Laura Fernández Maldonado6
  • Ramon Miralles Basseda6,7
  • Martha Kaznowski8
  • Adam Wichniak8
  • Vagioula Tsoutsi9
5 more authors
  • Pinelopi Kollia9
  • Marie De Saint-Hubert10,11
  • Anne Spinewine12,13
  • Nicolas Rodondi1,2
  • Carole Elodie Aubert1,2
13 affiliations
  1. 1Department of General Internal Medicine, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland
  2. 2Institute of Primary Healthcare (BIHAM), University of Bern, Bern, Switzerland
  3. 3Department of Clinical Research, University of Bern, Bern, Switzerland
  4. 4Department of Geriatric Medicine, Oslo University Hospital, Oslo, Norway
  5. 5Department of Old Age Psychiatry, Østfold Hospital Trust, Grålum, Norway
  6. 6Fundació Salut i Envelliment, Université autonome de Barcelone, Barcelona, Spain
  7. 7Department of Geriatric Medicine, Hospital Germans Trias i Pujol, Université Autonome de Barcelone, Barcelona, Spain
  8. 8Third Psychiatric Department and Sleep Medicine Centre, Institute of Psychiatry and Neurology, Warsaw, Poland
  9. 9Sleep Research Unit, First Department of Psychiatry, Eginition Hospital, Medical School, National & Kapodistrian University of Athens, Athens, Greece
  10. 10Institute of Health and Society (IRSS), Université catholique de Louvain, Brussels, Belgium
  11. 11Department of Geriatric Medicine, CHU UCL Namur, Yvoir, Belgium
  12. 12Louvain Drug Research Institute, Clinical Pharmacy & Pharmacoepidemiology Research Group, UCLouvain, Brussels, Belgium
  13. 13Pharmacy Department, CHU UCL Namur, Yvoir, Belgium
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Cite

BibTeXRIS
BibTeX
@article{kleinert2026implementing,
  title = {{Implementing a patient-centred and evidence-based intervention to reduce BEnzodiazepine and sedative-hypnotic use to improve patient SAFEty and quality of care (BE-SAFE): study protocol of a cluster randomised controlled trial}},
  author = {Maria-Lisa Kleinert and Sarah Atighetchi and Julia Isabel Beck and Lucy Bolt and Odile Stalder and Rita Romskaug and Enrico Callegari and Laura Fernández Maldonado and Ramon Miralles Basseda and Martha Kaznowski and Adam Wichniak and Vagioula Tsoutsi and Pinelopi Kollia and Marie De Saint-Hubert and Anne Spinewine and Nicolas Rodondi and Carole Elodie Aubert},
  journal = {BMJ Open},
  year = {2026},
  month = oct,
  doi = {10.1136/bmjopen-2026-123804},
  url = {https://bmjopen.bmj.com/lookup/doi/10.1136/bmjopen-2026-123804},
  note = {CC BY 4.0},
}
RIS
TY  - JOUR
TI  - Implementing a patient-centred and evidence-based intervention to reduce BEnzodiazepine and sedative-hypnotic use to improve patient SAFEty and quality of care (BE-SAFE): study protocol of a cluster randomised controlled trial
AU  - Maria-Lisa Kleinert
AU  - Sarah Atighetchi
AU  - Julia Isabel Beck
AU  - Lucy Bolt
AU  - Odile Stalder
AU  - Rita Romskaug
AU  - Enrico Callegari
AU  - Laura Fernández Maldonado
AU  - Ramon Miralles Basseda
AU  - Martha Kaznowski
AU  - Adam Wichniak
AU  - Vagioula Tsoutsi
AU  - Pinelopi Kollia
AU  - Marie De Saint-Hubert
AU  - Anne Spinewine
AU  - Nicolas Rodondi
AU  - Carole Elodie Aubert
PY  - 2026
DA  - 2026/10/12
JO  - BMJ Open
DO  - 10.1136/bmjopen-2026-123804
UR  - https://bmjopen.bmj.com/lookup/doi/10.1136/bmjopen-2026-123804
SN  - 2044-6055
SN  - 2044-6055
ER  -