Peer-reviewedPublisher termsScience Advances
A B1 SINE element within the mouse Malat1 long noncoding RNA acts as an internal ribosome entry site mediating micropeptide translation
9 affiliations
- 1Department of Microbiology, Immunology, and Molecular Genetics, University of California, Los Angeles, CA 90095, USA.
- 2Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT 06511, USA.
- 3Department of Biological Chemistry and Institute of Genomics and Proteomics, University of California, Los Angeles, CA 90095, USA.
- 4Department of Molecular, Cellular, and Developmental Biology, Yale University, New Haven, CT 06511, USA.
- 5Howard Hughes Medical Institute, Chevy Chase, MD 20815, USA.
- 6Department of Chemistry, Yale University, New Haven, CT 06511, USA.
- 7Molecular Biology Institute, University of California, Los Angeles, CA 90095, USA.
- 8Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research, University of California, Los Angeles, CA 90095, USA.
- 9Jonsson Comprehensive Cancer Center, David Geffen School of Medicine, University of California, Los Angeles, CA 90095, USA.
Related
- Cytoplasmic recapping commences the translation of a micropeptide, MARS from MALAT1 after the removal of an inhibitory RNA G-quadruplex
- Translation initiation by the Kozak mRNA sequence is based on a conformational readout on the ribosome
- An RNA Language Model trained on sequence alone reveals the structural logic of Internal Ribosome Entry Sites
- Viral control of translation: rise of the ribosome
- Fluorescent proteins misreport ribosome abundance under translation inhibition
BibTeX
@article{xiao2026sine,
title = {{A B1 SINE element within the mouse Malat1 long noncoding RNA acts as an internal ribosome entry site mediating micropeptide translation}},
author = {Wen Xiao and Tanja Hann and Zion Perry and Vijaya Pandey and Jeffrey Cheng and James Wohlschlegel and Anna Marie Pyle and Douglas L. Black},
journal = {Science Advances},
year = {2026},
month = oct,
doi = {10.1126/sciadv.aee5884},
url = {https://www.science.org/doi/10.1126/sciadv.aee5884},
}
RIS
TY - JOUR
TI - A B1 SINE element within the mouse Malat1 long noncoding RNA acts as an internal ribosome entry site mediating micropeptide translation
AU - Wen Xiao
AU - Tanja Hann
AU - Zion Perry
AU - Vijaya Pandey
AU - Jeffrey Cheng
AU - James Wohlschlegel
AU - Anna Marie Pyle
AU - Douglas L. Black
PY - 2026
DA - 2026/10/14
JO - Science Advances
DO - 10.1126/sciadv.aee5884
UR - https://www.science.org/doi/10.1126/sciadv.aee5884
SN - 2375-2548
ER -