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Peer-reviewedCC BY-NC-SASurgical neurology international

Spontaneous resolution of vestibular schwannoma: A singular phenomenon.

  • Rasha Hassan Noreldeen1
  • Miguel Ángel Arráez Sánchez2
  • Ossama Al-Mefty3
  1. 1Department of Neurosurgery, Mayo Clinic Rochester, Rochester, Minnesota, United States.
  2. 2Department of Neurosurgery, Regional University Hospital of Malaga, Malaga, Spain.
  3. 3Department of Neurosurgery, Mass General Brigham, Boston, Massachusetts, United States.
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Abstract

Background

The natural history of vestibular schwannoma (VS) is variable, with concerns about observation management rather than hearing loss. Shrinkage is well documented, with an undetermined hearing outcome.Case description

We report the case of a 62-year-old female followed in our clinic with a left cerebellopontine angle mass with radiological features of a VS. The mass underwent spontaneous total resolution while serviceable hearing was maintained for over 13 years, and we discuss the related pathophysiology.Conclusion

Spontaneous shrinkage of VSs is well documented in the literature. We present a rare case of complete spontaneous involution and loss of contrast enhancement, with preservation of serviceable hearing over a very long-term follow-up (13 years).

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Cite

BibTeXRIS
BibTeX
@article{noreldeen2026spontaneous,
  title = {{Spontaneous resolution of vestibular schwannoma: A singular phenomenon.}},
  author = {Rasha Hassan Noreldeen and Miguel Ángel Arráez Sánchez and Ossama Al-Mefty},
  journal = {Surgical neurology international},
  year = {2026},
  month = oct,
  doi = {10.25259/sni_1078_2025},
  url = {https://europepmc.org/article/MED/42974231},
  note = {CC BY-NC-SA},
}
RIS
TY  - JOUR
TI  - Spontaneous resolution of vestibular schwannoma: A singular phenomenon.
AU  - Rasha Hassan Noreldeen
AU  - Miguel Ángel Arráez Sánchez
AU  - Ossama Al-Mefty
PY  - 2026
DA  - 2026/10/09
JO  - Surgical neurology international
DO  - 10.25259/sni_1078_2025
UR  - https://europepmc.org/article/MED/42974231
AB  - Background  The natural history of vestibular schwannoma (VS) is variable, with concerns about observation management rather than hearing loss. Shrinkage is well documented, with an undetermined hearing outcome.Case description  We report the case of a 62-year-old female followed in our clinic with a left cerebellopontine angle mass with radiological features of a VS. The mass underwent spontaneous total resolution while serviceable hearing was maintained for over 13 years, and we discuss the related pathophysiology.Conclusion  Spontaneous shrinkage of VSs is well documented in the literature. We present a rare case of complete spontaneous involution and loss of contrast enhancement, with preservation of serviceable hearing over a very long-term follow-up (13 years).
SN  - 2229-5097
SN  - 2152-7806
ER  -