An automated operon refactoring workflow for heterologous expression of non-ribosomal peptide biosynthetic…

Preserving a decade of machine-learning validity across a ground-up refactoring: a five-tier automated validation of RCT-Reviewer, an independent modernization of RobotReviewer
V. Sahu, A. Sahu
medRxiv8 Sep 2026PreprintCC BYFull textEpidemiology & public healthmedRxiv
High diversity but limited expression of biosynthetic gene clusters in a peatland microbial community
Zander Rainier Human, Rene Hoover, Clara Chan +2
Nature Communications6 Oct 2026Peer-reviewedCC BY 4.0Full textPharmacology & toxicologyCrossref
Heterologous Reconstitution of 4-Amidopentadienoate Biosynthesis Identifies the PKS Machinery Responsible for Warhead Formation
M. Tvilum, J. L. Veiler, T. T. Paulsen +6
bioRxiv17 Sep 2026PreprintCC BY-NC-NDFull textPharmacology & toxicologybioRxiv
Sertoli-Leydig Cell Tumour With Heterologous Elements Presenting as Hyperandrogenaemia and Markedly Elevated Alpha-Fetoprotein: A Challenging Diagnosis.
Baraa Albousen, Joseph Mechery
Cureus24 Sep 2026Peer-reviewedCC BYFull textObstetrics, gynaecology & paediatricsEurope PMC
Perturbation of 60 S Ribosomal Biogenesis Results in Ribosomal Protein L5- and L11-dependent p53 Activation
Xiao-Xin Sun, Yue-Gang Wang, Dimitris Xirodimas +1
Journal of Biological Chemistry16 Sep 2026Peer-reviewedCC BYFull text80 citedOncologyHAL

Cite

BibTeX

@article{li2026automated,
  title = {{An automated operon refactoring workflow for heterologous expression of non-ribosomal peptide biosynthetic gene clusters}},
  author = {Zhibo Li and Lifu Liu and Xingyan Sun and Hui Wu and Shiquan Fu and Jiao Jin and Yangming Zhang and Xiyan Zhang and Zishuo Zeng and Zhiyin Tao and Ningxin Chen and Xinran Wang and Jianming Lv and Pan Luo and Dan Hu and Hao Gao and Jay D. Keasling and Xiaozhou Luo},
  journal = {Nature Communications},
  year = {2026},
  month = oct,
  doi = {10.1038/s41467-026-78648-w},
  url = {https://www.nature.com/articles/s41467-026-78648-w},
  note = {CC BY-NC-ND 4.0},
}

RIS

TY  - JOUR
TI  - An automated operon refactoring workflow for heterologous expression of non-ribosomal peptide biosynthetic gene clusters
AU  - Zhibo Li
AU  - Lifu Liu
AU  - Xingyan Sun
AU  - Hui Wu
AU  - Shiquan Fu
AU  - Jiao Jin
AU  - Yangming Zhang
AU  - Xiyan Zhang
AU  - Zishuo Zeng
AU  - Zhiyin Tao
AU  - Ningxin Chen
AU  - Xinran Wang
AU  - Jianming Lv
AU  - Pan Luo
AU  - Dan Hu
AU  - Hao Gao
AU  - Jay D. Keasling
AU  - Xiaozhou Luo
PY  - 2026
DA  - 2026/10/11
JO  - Nature Communications
DO  - 10.1038/s41467-026-78648-w
UR  - https://www.nature.com/articles/s41467-026-78648-w
SN  - 2041-1723
ER  -

Related

Cite