Postcardiotomy extracorporeal life support after isolated or valve-concomitant coronary artery bypass grafting: An observational multicenter study
Abstract
Objectives: Data on outcomes of patients undergoing isolated coronary artery bypass grafting (isolated CABG) versus CABG and concomitant left heart valve (LHV-CABG) surgery are conflicting, especially in extracorporeal life support (ECLS) settings. We compared characteristics, in-hospital outcomes, and overall survival between patients undergoing isolated-CABG and concomitant LHV-CABG requiring postcardiotomy ECLS from a large multicenter study. Methods: This retrospective, multicenter (34 centers), observational study included adults requiring postcardiotomy ECLS between 2000 and 2020. Clinical characteristics and outcomes were compared between patients who underwent isolated CABG with those who underwent LHV-CABG. Association between type of surgery and in-hospital survival was investigated through mixed-Cox proportional hazards models. Results: = .210) for isolated CABG and LHV-CABG groups, respectively. Conclusions: LHV-CABG surgery, compared with isolated CABG, was associated with higher in-hospital mortality in patients requiring ECLS, whereas no midterm postdischarge survival differences could be detected. Early identification of patients in need for ECLS following LHV-CABG may improve outcomes.
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BibTeX
@article{mariani2026postcardiotomy,
title = {{Postcardiotomy extracorporeal life support after isolated or valve-concomitant coronary artery bypass grafting: An observational multicenter study}},
author = {Silvia Mariani and Sacha Matteucci and Bas van Bussel and Anne-Kristin Schaefer and Diyar Saeed and Matteo Pozzi and Luca Botta and Nikolaos Kalampokas and Agne Jankuviene and Karl Bounader and Xiaotong Hou and Jeroen Bunge and Hergen Buscher and Leonardo Salazar and Bart Meyns and Michael Mazzeffi and Sandro Sponga and Vitaly Sorokin and Claudio Russo and Michele Di Mauro and Pranya Sakiyalak and Antonio Fiore and Daniele Camboni and Giuseppe Maria Raffa and Rodrigo Diaz and I-Wen Wang and Jae-Seung Jung and Jan Belohlavek and Vin Pellegrino and Giacomo Bianchi and Matteo Pettinari and Alessandro Barbone and José Garcia and Kiran Shekar and Glenn Whitman and Francesco Formica and Roberto Lorusso and Bas C.T. van Bussel and Jeroen J.H. Bunge},
journal = {Journal of Thoracic and Cardiovascular Surgery open},
year = {2026},
month = sep,
doi = {10.1016/j.xjon.2026.101875},
url = {https://hal.science/hal-05749391v1},
note = {CC BY},
}
RIS
TY - JOUR
TI - Postcardiotomy extracorporeal life support after isolated or valve-concomitant coronary artery bypass grafting: An observational multicenter study
AU - Silvia Mariani
AU - Sacha Matteucci
AU - Bas van Bussel
AU - Anne-Kristin Schaefer
AU - Diyar Saeed
AU - Matteo Pozzi
AU - Luca Botta
AU - Nikolaos Kalampokas
AU - Agne Jankuviene
AU - Karl Bounader
AU - Xiaotong Hou
AU - Jeroen Bunge
AU - Hergen Buscher
AU - Leonardo Salazar
AU - Bart Meyns
AU - Michael Mazzeffi
AU - Sandro Sponga
AU - Vitaly Sorokin
AU - Claudio Russo
AU - Michele Di Mauro
AU - Pranya Sakiyalak
AU - Antonio Fiore
AU - Daniele Camboni
AU - Giuseppe Maria Raffa
AU - Rodrigo Diaz
AU - I-Wen Wang
AU - Jae-Seung Jung
AU - Jan Belohlavek
AU - Vin Pellegrino
AU - Giacomo Bianchi
AU - Matteo Pettinari
AU - Alessandro Barbone
AU - José Garcia
AU - Kiran Shekar
AU - Glenn Whitman
AU - Francesco Formica
AU - Roberto Lorusso
AU - Bas C.T. van Bussel
AU - Jeroen J.H. Bunge
PY - 2026
DA - 2026/09/14
JO - Journal of Thoracic and Cardiovascular Surgery open
DO - 10.1016/j.xjon.2026.101875
UR - https://hal.science/hal-05749391v1
AB - Objectives: Data on outcomes of patients undergoing isolated coronary artery bypass grafting (isolated CABG) versus CABG and concomitant left heart valve (LHV-CABG) surgery are conflicting, especially in extracorporeal life support (ECLS) settings. We compared characteristics, in-hospital outcomes, and overall survival between patients undergoing isolated-CABG and concomitant LHV-CABG requiring postcardiotomy ECLS from a large multicenter study. Methods: This retrospective, multicenter (34 centers), observational study included adults requiring postcardiotomy ECLS between 2000 and 2020. Clinical characteristics and outcomes were compared between patients who underwent isolated CABG with those who underwent LHV-CABG. Association between type of surgery and in-hospital survival was investigated through mixed-Cox proportional hazards models. Results: = .210) for isolated CABG and LHV-CABG groups, respectively. Conclusions: LHV-CABG surgery, compared with isolated CABG, was associated with higher in-hospital mortality in patients requiring ECLS, whereas no midterm postdischarge survival differences could be detected. Early identification of patients in need for ECLS following LHV-CABG may improve outcomes.
SN - 2666-2736
SN - 2666-2736
ER -