Perioperative and persistent opioid use after surgery: a scoping review
Abstract
Persistent opioid use after surgery is a growing concern, with existing reviews lacking strong predictors beyond prior opioid use. This scoping review aimed to identify knowledge gaps for future research, particularly regarding the impact of the perioperative period (including preoperative, intraoperative, and postoperative) opioid use on persistent opioid use after surgery. A comprehensive database search of prospective studies explored the association between perioperative opioid use and persistent use in adults after surgery. From the 21 identified studies, we found a complex relationship between perioperative opioid use and persistent use. Preoperative opioid use correlated with persistent use, but the impact of intraoperative and short-term postoperative use remained unclear. Interestingly, postoperative prescriptions at 3 months predicted a higher risk of persistent use at 6 and 12 months. These findings highlight the need for further research to explore the mediating factors that increase the risk of persistent use among preoperative opioid users, along with the specific roles of intraoperative and postsurgical inpatient opioid consumption, and short-term postoperative opioid prescriptions (≤30 days).
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BibTeX
@article{almodibeg2026perioperative,
title = {{Perioperative and persistent opioid use after surgery: a scoping review}},
author = {Bader Almodibeg and Jungwoo Kang and Patrice Forget},
journal = {British Journal of Anaesthesia open},
year = {2026},
month = oct,
doi = {10.1016/j.bjao.2025.100412},
url = {https://hal.science/hal-05805517v1},
note = {CC BY-NC-ND 4.0},
}
RIS
TY - JOUR
TI - Perioperative and persistent opioid use after surgery: a scoping review
AU - Bader Almodibeg
AU - Jungwoo Kang
AU - Patrice Forget
PY - 2026
DA - 2026/10/19
JO - British Journal of Anaesthesia open
DO - 10.1016/j.bjao.2025.100412
UR - https://hal.science/hal-05805517v1
AB - Persistent opioid use after surgery is a growing concern, with existing reviews lacking strong predictors beyond prior opioid use. This scoping review aimed to identify knowledge gaps for future research, particularly regarding the impact of the perioperative period (including preoperative, intraoperative, and postoperative) opioid use on persistent opioid use after surgery. A comprehensive database search of prospective studies explored the association between perioperative opioid use and persistent use in adults after surgery. From the 21 identified studies, we found a complex relationship between perioperative opioid use and persistent use. Preoperative opioid use correlated with persistent use, but the impact of intraoperative and short-term postoperative use remained unclear. Interestingly, postoperative prescriptions at 3 months predicted a higher risk of persistent use at 6 and 12 months. These findings highlight the need for further research to explore the mediating factors that increase the risk of persistent use among preoperative opioid users, along with the specific roles of intraoperative and postsurgical inpatient opioid consumption, and short-term postoperative opioid prescriptions (≤30 days).
SN - 2772-6096
ER -