Associations between psychiatric comorbidity and intensive care unit length of stay, hospital length of stay, and in‐hospital mortality: A retrospective observational study
5 affiliations
- 1Department of Psychiatry Shinshu University School of Medicine Matsumoto Nagano Japan.
- 2Department of Community Mental Health Shinshu University School of Medicine Matsumoto Nagano Japan.
- 3Division of Gastroenterological, Hepato-Biliary-Pancreatic, Transplantation and Pediatric Surgery, Department of Surgery Shinshu University School of Medicine Matsumoto Nagano Japan.
- 4Department of Emergency and Critical Care Medicine Shinshu University School of Medicine Matsumoto Nagano Japan.
- 5Department of Pathology of Mental Diseases National Institute of Mental Health, National Center of Neurology and Psychiatry Kodaira Tokyo Japan.
Abstract
Aim
Psychiatric comorbidities are common among patients admitted to the intensive care unit (ICU), but findings regarding their impact on clinical outcomes remain inconsistent. Additionally, existing studies have often included patients admitted for suicide attempts or self-harm, leaving insufficient evidence about the independent effects of psychiatric comorbidity on clinical outcomes. To address this gap, this study investigated the independent association of psychiatric comorbidity with ICU length of stay, hospital length of stay, and in-hospital mortality among patients admitted to the ICU, excluding those admitted for suicide attempts or self-harm.Methods
Of the 2599 patients admitted to the ICU of a university hospital, 2192 were included in the analysis. After adjusting for age, sex, body mass index, admission category, and severity score, generalized linear models were used to evaluate ICU and hospital length of stay, and logistic regression analysis was used to assess in-hospital mortality.Results
Among the 2192 patients included in the analysis, 75 had psychiatric comorbidity. In adjusted analyses, psychiatric comorbidity was not significantly associated with ICU length of stay, hospital length of stay, or in-hospital mortality.Conclusion
No participants were admitted to the ICU for suicide attempts or self-harm, and psychiatric comorbidity was not an independent predictor of ICU length of stay, hospital length of stay, or in-hospital mortality. Thus, in this ICU population, no statistically significant association was detected between psychiatric comorbidity and short-term clinical outcomes. Therefore, caution is needed when estimating ICU outcomes based solely on the presence of psychiatric comorbidity.
Related
- Sexual dysfunction after female genital mutilation/cutting: A retrospective cross-sectional study of associations with organ-specific genital anatomy, trauma history, and psychiatric comorbidity
- Prenatal cannabis use disorder and postpartum psychiatric emergency department visits: A retrospective cohort study of trends and associations in California, 2016–2021
- Prevalence and Associated Factors of Opioid Withdrawal Syndrome in Adults Admitted to an Intensive Care Unit: A Retrospective Observational Descriptive Study
- Acid-sensing ion channels in pain and psychiatric disorders: from basic properties to comorbidity mechanisms
- Understanding non-psychiatric nurses' experiences of caring for patients with mental-physical comorbidity: a descriptive phenomenological study.
BibTeX
@article{nakamura2026associations,
title = {{Associations between psychiatric comorbidity and intensive care unit length of stay, hospital length of stay, and in‐hospital mortality: A retrospective observational study}},
author = {Toshinori Nakamura and Takumi Momma and Tomonari Yoshizawa and Yusuke Arai and Daimei Sasayama and Atsuyoshi Mita and Hiroshi Imamura and Ryota Hashimoto and Shinsuke Washizuka},
journal = {PCN reports : psychiatry and clinical neurosciences},
year = {2026},
month = nov,
doi = {10.1002/pcn5.70439},
url = {https://europepmc.org/article/PMC/PMC13725844},
note = {CC BY},
}
RIS
TY - JOUR
TI - Associations between psychiatric comorbidity and intensive care unit length of stay, hospital length of stay, and in‐hospital mortality: A retrospective observational study
AU - Toshinori Nakamura
AU - Takumi Momma
AU - Tomonari Yoshizawa
AU - Yusuke Arai
AU - Daimei Sasayama
AU - Atsuyoshi Mita
AU - Hiroshi Imamura
AU - Ryota Hashimoto
AU - Shinsuke Washizuka
PY - 2026
DA - 2026/11/02
JO - PCN reports : psychiatry and clinical neurosciences
DO - 10.1002/pcn5.70439
UR - https://europepmc.org/article/PMC/PMC13725844
AB - Aim Psychiatric comorbidities are common among patients admitted to the intensive care unit (ICU), but findings regarding their impact on clinical outcomes remain inconsistent. Additionally, existing studies have often included patients admitted for suicide attempts or self-harm, leaving insufficient evidence about the independent effects of psychiatric comorbidity on clinical outcomes. To address this gap, this study investigated the independent association of psychiatric comorbidity with ICU length of stay, hospital length of stay, and in-hospital mortality among patients admitted to the ICU, excluding those admitted for suicide attempts or self-harm.Methods Of the 2599 patients admitted to the ICU of a university hospital, 2192 were included in the analysis. After adjusting for age, sex, body mass index, admission category, and severity score, generalized linear models were used to evaluate ICU and hospital length of stay, and logistic regression analysis was used to assess in-hospital mortality.Results Among the 2192 patients included in the analysis, 75 had psychiatric comorbidity. In adjusted analyses, psychiatric comorbidity was not significantly associated with ICU length of stay, hospital length of stay, or in-hospital mortality.Conclusion No participants were admitted to the ICU for suicide attempts or self-harm, and psychiatric comorbidity was not an independent predictor of ICU length of stay, hospital length of stay, or in-hospital mortality. Thus, in this ICU population, no statistically significant association was detected between psychiatric comorbidity and short-term clinical outcomes. Therefore, caution is needed when estimating ICU outcomes based solely on the presence of psychiatric comorbidity.
SN - 2769-2558
ER -